Sökning: "IL-18"

Visar resultat 1 - 5 av 6 uppsatser innehållade ordet IL-18.

  1. 1. Upregulation of CLIC1 gene in THP1 cells stimulated by lipopolysaccharides

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Karldiony Roskvist; [2021]
    Nyckelord :;

    Sammanfattning : The NLRP3 inflammasome is a multiprotein complex that controls caspase-1 activation and the development of the pro-inflammatory cytokines IL-1 and IL-18, as well as pyroptosis. The NLRP3 inflammasome in murine macrophages is normally triggered by pathogen-associated molecular patterns as well as a variety of structurally unrelated stimuli. LÄS MER

  2. 2. A study of the effect of digitoxin on the immune response of panc-1 cell line compared to BxPC-3 cell line in vitro

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsovetenskaper

    Författare :Salwa Chehab Eddine; [2021]
    Nyckelord :;

    Sammanfattning : This project had a focus on the effect of digitoxin on inflammation in cancer Panc-1 cell line compared to BxPC-3 cell line. Pancreatic cancer, especially the form pancreatic adenocarcinoma is the fourth cause for cancer deaths, seen in the Western world. LÄS MER

  3. 3. microRNA-200 Family Expression Level Changes in Stimulated THP-1 Cells Following NLRP3 Inflammasome Activation

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Kristina Backlund; [2020]
    Nyckelord :;

    Sammanfattning : Innate immunity is the immune systems rapid responses to infection after being attacked by a pathogen. Inflammatory responses are activated by the detection of pathogen-associated molecular patterns and danger-associated molecular patterns through pattern recognition receptors on inflammatory cells. LÄS MER

  4. 4. Activation of NLRP3 inflammasome leads to the differential secretion of interleukins 1*/18 possibly linked to pyroptosis in THP-1 cells

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Jana Damiani; [2020]
    Nyckelord :;

    Sammanfattning : Organisms are constantly exposed to microorganisms, some of which can cause disease, and yet, sickness only rarely occurs. Upon infection, the immune system is mobilized to eliminate the threat and re-establish homeostasis. LÄS MER

  5. 5. BABAM1 regulation of NLRP3 inflammasome in THP-1 monocyte-like cell lines

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Musa Marrah; [2020]
    Nyckelord :;

    Sammanfattning : The nucleotide-binding oligomerization domain–like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a group of multi-protein complex that mediates immune responses through the production of biologically active IL-1β and IL-18. Dysregulation of NLRP3 inflammasome has been linked to various diseases associated with infection, inflammation, and cancer. LÄS MER