Sökning: "Individual Case Safety Reports"

Visar resultat 1 - 5 av 10 uppsatser innehållade orden Individual Case Safety Reports.

1. 1. Virtual Reality för en säkrare arbetsplats : Virtual Reality som en undervisningsmetod i säkerhetsutbildningen

   Kandidat-uppsats, KTH/Byggteknik och design

   Författare :Adam Abdurahman; Moustapha Chouhad; [2022]
   Nyckelord :;

   Sammanfattning : The construction industry is slowly approaching the middle of this century, but not enoughattention is being given to safety work. There are still far too many people who are injured attheir workplaces both in Sweden and abroad. LÄS MER

3. 2. Free-text Informed Duplicate Detection of COVID-19 Vaccine Adverse Event Reports

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för systemteknik

   Författare :Erik Turesson; [2022]
   Nyckelord :Duplicate detection; Deduplication; Record linkage; Adverse Event Reports; COVID-19 Vaccines; Uppsala Monitoring Centre; VigiBase; Machine Learning; Gradient Boosted Decision Trees; BERT; Natural Language Processing; Pharmacovigilance; Individual Case Safety Reports;

   Sammanfattning : To increase medicine safety, researchers use adverse event reports to assess causal relationships between drugs and suspected adverse reactions. VigiBase, the world's largest database of such reports, collects data from numerous sources, introducing the risk of several records referring to the same case. LÄS MER

4. 3. Reaching Those ‘Out-of-Reach’: An Explorative Case-Study of Fire Prevention in Vulnerable Urban Communities within Copenhagen.

   Master-uppsats, Lunds universitet/Riskhantering (CI)

   Författare :Aron Fransson; [2021]
   Nyckelord :Fire Prevention; Fire Rescue Services; Risk Communication; Fire Governance; Urban Vulnerable Communities; Community Risk Reduction; Technology and Engineering;

   Sammanfattning : Considering the nature of vulnerability to fires and at-risk groups, the issue is arguably a social problem where spatial analysis has allowed for a greater context, beyond the individual, to be analyzed. Furthermore, reports from fire rescue services of local safety concerns and the convergence of interest between different stakeholders has made communities disposition to fire safety increasingly relevant. LÄS MER

5. 4. Creation of a Next-Generation Standardized Drug Groupingfor QT Prolonging Reactions using Machine Learning Techniques

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för systemteknik

   Författare :Jacob Tiensuu; Elsa Rådahl; [2021]
   Nyckelord :Pharmacovigilance; Adverse Drug Reactions; MedDRA; VigiBase; WHODrug Global; QT prolongation; Torsades de Pointes; Individual Case Safety Reports; Text Recognition; Standardised Drug Grouping; Multinomial Logistic Regression; BERT;

   Sammanfattning : This project aims to support pharmacovigilance, the science and activities relating to drug-safety and prevention of adverse drug reactions (ADRs). We focus on a specific ADR called QT prolongation, a serious reaction affecting the heartbeat. Our main goal is to group medicinal ingredients that might cause QT prolongation. LÄS MER

7. 5. Improving the speed and quality of an Adverse Event cluster analysis with Stepwise Expectation Maximization and Community Detection

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för medicinska vetenskaper

   Författare :Nils Erlanson; [2020]
   Nyckelord :Adverse Drug Reactions; Pharmacovigilance; Cluster Analysis; Stepwise Expectation Maximization; Community Detection; Topic Modelling;

   Sammanfattning : Adverse drug reactions are unwanted effects alongside the intended benefit of a drug and might be responsible for 3-7\% of hospitalizations. Finding such reactions is partly done by analysing individual case safety reports (ICSR) of adverse events. The reports consist of categorical terms that describe the event. LÄS MER