Sökning: "Injectable"

Visar resultat 1 - 5 av 17 uppsatser innehållade ordet Injectable.

  1. 1. Tuning physical and chemical attributes of the synthetic implant poly(L-lactic acid) and its effects on biological stimulation

    Kandidat-uppsats,

    Författare :Gabriella Sverlinger; Felicia Norman; Nora Othman; Wilma Hämäläinen; Michaela Thyberg; Maja Jonsson; [2023]
    Nyckelord :Polylactic acid; degradation rate of PLLA; physio- chemical properties of PLA; injectable PLLA;

    Sammanfattning : Poly(lactic acid) (PLA) is a polymer chain consisting of repeating units of lactic acid (LA) used in various biomedical applications because of its biocompatible features. It is commonly used as a subdermal filler and constitutes as the main ingredient in SculptraR, which is a collagen regenerating filler used to treat lipoatrophy of the cheeks or to rejuvenate the skin. LÄS MER

  3. 2. Study of surfactant-preservative and protein-preservative interactions in multi-dose injectable formulation

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Javier Lagares Martín; [2023]
    Nyckelord :Phenol; polysorbate 80; cloud point; somatropin; aggregation; titration; light scattering; salt; surfactant; preservative; protein; tonicity adjusting agents; multi-dose injectable formulation; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : Multidose injectable formulations require a preservative such as phenol to ensure sterility and protection against microbial contamination during clinical use. However, it is known that the interaction between these components and non-ionic surfactants such as polysorbate 80, also found in this type of formulations, present incompatibilities, which can lead to decreases in the efficacy of the product. LÄS MER

  4. 3. A viscoelastic evaluation of an injectable disulfide cross-linked thiol-collagen hydrogel: for tissue bulking post-myocardial infarction to prevent heart failure

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Makromolekylär kemi

    Författare :Karin Dungner; [2023]
    Nyckelord :;

    Sammanfattning : Cardiovascular diseases are currently the leading cause of death globally. Progression of the disease affects the composition and function of the heart and in many cases subsequently results in heart failure over time where a heart transplant is vital. Therefore, there is a need for medical treatments to stop the progression of the disease. LÄS MER

  5. 4. Injectable and shape-retaining collagen hydrogel, crosslinked using bio-orthogonal cycloaddition chemistry

    Master-uppsats, KTH/Fiber- och polymerteknologi

    Författare :Murtaza Sharq; [2022]
    Nyckelord :Injectable and shape-retaining collagen hydrogel; crosslinked using bio-orthogonal cycloaddition chemistry; Injicerbara och formbevarande kollagenhydrogeler; tvärbundna med bio-ortagonal cykloadditionskemi;

    Sammanfattning : Under senaste decennierna, har intresset kring implantat från naturliga och syntetiska polymerer ökat markant i samband med en ökad marknadsefterfrågan på vävnadsdonationer. Detta har lett till efterforskningen av nya in-situ formerande geler med formbevarande egenskaper in-vivo. LÄS MER

  7. 5. Phenol-Protein Solution Stability

    Magister-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Johan Sjölund; [2022]
    Nyckelord :Phenol; Protein; Proteins; Lysozyme; Betalactoglobulin; Trastuzumab; Lipase; GAZ; GA-Z; Palifermin; Titration; Probedrum; Pharmaceutical Technology; Chemistry;

    Sammanfattning : Phenol is a commonly used preservative in pharmaceutical protein solutions. It is compatible with most proteins but can cause aggregation and denaturation at higher concentrations or in more sensitive proteins. LÄS MER