Sökning: "Johannes Pohl"

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  1. 1. Thyroid Endocrine Disruption of Propylparaben Assessed Using an Optimized Individual Xenopus tropicalis Metamorphosing Tadpole Exposure System

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Johannes Pohl; [2015]
    Nyckelord :Xenopus; Thyroid hormones; Endocrine disruption; Amphibian metamorphosis assay; Propylparaben; Hormonstörande ämnen; Propylparaben; Xenopus; Sköldkörtelhormoner;

    Sammanfattning : The anuran Xenopus tropicalis tadpole is an attractive model animal in toxicological evaluation of suspected thyroid disrupting xenobiotics. Due to its reliance of a functioning hypothalamic-pituitary-thyroid (HPT) axis for normal metamorphosis, effects on the HPT axis produces apical endpoints, which are easy to measure. LÄS MER