Sökning: "KRAS"

Visar resultat 1 - 5 av 8 uppsatser innehållade ordet KRAS.

  1. 1. APC, BRAF and KRAS mutations, and MLH1, MGMT and CDKN2A expression analysis in Nepalese colorectal cancer patients. : -

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Alireza Nourizadeh; [2017]
    Nyckelord :Colorectal cancer CRC ; Formalin fixed paraffin embedded FFPE ; APC; KRAS; BRAF; polymerase chain reaction PCR ; MLH1; MGMT; CDKN2A; quantitative polymerase chain reaction qPCR ; hotspot; expression profiling.;

    Sammanfattning : Colorectal cancer (CRC) is a common malignancy which develops due to old age and lifestyle factors, low percent of patients afflicted by a genetic disorders. Half of all colorectal cancer patients are diagnosed after metastasis. LÄS MER

  3. 2. Drömmar i kras : Analys av glasfragment från Birkas hamn

    Kandidat-uppsats, Stockholms universitet/Arkeologiska forskningslaboratoriet

    Författare :Bjarne Däcker; [2016]
    Nyckelord :Birka XRF glass;

    Sammanfattning : This essay reports from a study using XRF of thirteen glass fragments found in the harbour of the Viking town of Birka some interesting observations were made. Two fragments are coloured using antimony and manganese. One fragment could have been made using wood ash glass. LÄS MER

  4. 3. Analysis of PIK3CA mutations in tumours from patients with non-small cell lung cancer using pyrosequencing

    Kandidat-uppsats, Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Författare :Jennifer Jonasson; [2014]
    Nyckelord :PI3K; tumour marker; pseudogene; oncogene; targeted therapy;

    Sammanfattning : A subgroup of non-small cell lung cancer (NSCLC) cases harbour mutations in classical oncogenes, which can affect therapy response and prognosis. By therapeutically targeting the corresponding proteins with inhibitory drugs, the clinical outcome for these lung cancer patients may be improved. LÄS MER

  5. 4. Molekylär klassificering av tjocktarmscancer : PAM-klusteranalys för identifiering av undergrupper

    Kandidat-uppsats, Statistik

    Författare :Per Arvidsson; Samuel Snickars; [2012]
    Nyckelord :klusteranalys; tjocktarmscancer; PAM-klusteranalys; CIMP; MSI; BRAF; KRAS; undergrupper;

    Sammanfattning : The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. LÄS MER

  7. 5. WT1 påverkar proliferationen för cancercellinjer troligen via reglering av c-Myc

    Uppsats för yrkesexamina på grundnivå, Biomedicinsk laboratorievetenskap

    Författare :Jonathan Eriksson; [2011]
    Nyckelord :WT1; proliferation; c-Myc; nedtystning; nedreglering; KRAS;

    Sammanfattning : .... LÄS MER