Sökning: "Kirsten Mattsson"

Hittade 1 uppsats innehållade orden Kirsten Mattsson.

  1. 1. Genetic heterogeneity of EGFR and KRAS mutations in primary tumor tissue from non-small cell lung cancer patients

    Magister-uppsats, Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Johanna Mattsson; [2011]
    Nyckelord :Non-small cell lung cancer; KRAS; EGFR; heterogeneity; mutation;

    Sammanfattning : Activated epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations characterize molecular subgroups of non-small cell lung cancer (NSCLC) and have a strong predictive value for response to EGFR inhibitor therapy. Recently, EGFR mutation testing was included in the diagnostic algorithm of NSCLC. LÄS MER