Sökning: "Lana Faradj"

Hittade 1 uppsats innehållade orden Lana Faradj.

  1. 1. Improving Caco-2 cell permeability assay using phospholipid covered silica beads

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaci

    Författare :Lana Faradj; [2021]
    Nyckelord :permeability; Caco-2; recovery; lipophilic; phosphatidylcholine; silica beads; peptide; plastic binding; bovine serum albumin;

    Sammanfattning : The Caco-2 cell assay is widely used for in vitro permeability measurements. However, a draw back with the assay that this study will focus on improving, is compound adsorption to the plastic material. Lipophilic compounds such as Cyclosporin A and Peptide J, that will be used in this study, tend to bind to the plastic material in the assay. LÄS MER