Sökning: "M protein"

Visar resultat 1 - 5 av 91 uppsatser innehållade orden M protein.

  1. 1. Integrating web data miningand machine learningalgorithms to predict progression free survival and overall survival in multiple myeloma patients

    Master-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Yijie Zhou; [2023]
    Nyckelord :;

    Sammanfattning : Multiple myeloma patients have highly variable progression free survival and overall survivalranging from a few weeks to more than 5 years. Stratification of these patients can help toidentify high risk patients i-e patients with short-term progression free survival and overallsurvival. LÄS MER

  3. 2. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Alexandra Johannesson; [2023]
    Nyckelord :neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Sammanfattning : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. LÄS MER

  4. 3. Concentration of Proteins and Decrease of Salt Content in a Hydrolyzed Fermentation Broth Using Membrane Filtration

    Master-uppsats, Lunds universitet/Kemiteknik (CI)

    Författare :Linnea Sjökvist; [2023]
    Nyckelord :Membrane filtration; ultrafiltration; PHA; polyhydroxyalkanoates; chemical engineering; Technology and Engineering;

    Sammanfattning : Membrane filtration was used to concentrate proteins and decrease the salt concentration in a hydrolyzed fermentation broth. The broth was a by-product from the bacterial production and extraction of polyhydroxyalkanoates (PHA), that can be used to produce biobased plastics. LÄS MER

  5. 4. Exploring a unique pocket in Galectin-8N by the synthesis of D-galactoside-based benzimidazole inhibitors

    Master-uppsats, Lunds universitet/Centrum för analys och syntes

    Författare :Sid Bartold; [2023]
    Nyckelord :organic chemistry; synthesis; gal; gal-8; gal-8N; galectin; galectin-8; galectin-8N; inhibitor; drug development; benzimidazole; galactoside; carbohydrate; carbohydrate chemistry; Suzuki-coupling; Chemistry;

    Sammanfattning : Galectins are a family of glycan-binding proteins where galectin-8 is a part of the subgroup known as tandem-repeat type galectins. Galectin-8 is composed of two homologous CRDs, one N- and one C-terminal CRD. As it stands now, galectin-8N has been found to bind to a larger number of glycans than galectin-8C. LÄS MER

  7. 5. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Neuroonkologi och neurodegeneration

    Författare :Mathilda Stigenberg; [2023]
    Nyckelord :cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Sammanfattning : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. LÄS MER