Sökning: "Mantle cell lymphoma MCL"

Hittade 5 uppsatser innehållade orden Mantle cell lymphoma MCL.

  1. 1. Action of CB1 and CB2 antagonists/inverse agonists on mantle cell lymphoma

    Master-uppsats, Akademin för hållbar samhälls- och teknikutveckling

    Författare :Daniel Chui; [2011]
    Nyckelord :cannabinoid; mantle; lymphoma; hemopressin; anandamide; thc;

    Sammanfattning : In this study, the effects of antagonists to the cannabinoid receptors in MCL cell lines were studied. Results presented in this study show that signalling through cannabinoid receptor with antagonists such as SR141716, SR144528 decreases cell viability but hemopressin when analyzing with XTT. LÄS MER

  3. 2. Action of CB1 and CB2 antagonists/inverse agonists on mantle cell lymphoma

    Master-uppsats, Akademin för hållbar samhälls- och teknikutveckling

    Författare :Daniel Chui; [2011]
    Nyckelord :;

    Sammanfattning : In this study, the effects of antagonists to the cannabinoid receptors in MCL cell lines were studied. Results presented in this study show that signalling through cannabinoid receptor with antagonists such as SR141716, SR144528 decreases cell viability but hemopressin when analyzing with XTT. LÄS MER

  4. 3. Treatment of a mantle cell lymphoma cell line with cannabinoids and cytostatics : - effects on DNA synthesis and ceramide metabolism

    Master-uppsats, Akademin för hållbar samhälls- och teknikutveckling; Institutionen för biologi och kemiteknik

    Författare :Ablahad Chabo; [2009]
    Nyckelord :cancer; mantle cell lymphoma; cannabinoids; cytostatics; ceramide;

    Sammanfattning : Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy with bad prognosis, which predominates in males with advanced age. However, studies of the endocannabinoid system and how it affects tumour behaviour provides the basis for designing innovative therapeutic strategies that could open new opportunities for treatment of patient with MCL. LÄS MER

  5. 4. Development and characterization of Mantle Cell Lymphoma specific IgGs

    Magister-uppsats, Institutionen för fysik, kemi och biologi

    Författare :Katarina Gärdefors; [2008]
    Nyckelord :Mantle cell lymphoma MCL ; Sox11; human recombinant antibodies; single chain variable fragment scFv ; IgG.;

    Sammanfattning : Mantle cell lymphoma (MCL) is one of several sub-types of B-cell lymphomas. The malignancy is very aggressive and average survival time is short. The hallmark of MCL is over expression of cyclin D1, however about 15% of all MCL cases do not display this over expression and are easily misdiagnosed. LÄS MER

  7. 5. Effect of combined treatment with R-(+)-methanandamide and chemotherapeutic drugs in mantle cell lymphoma and chronic lymphocytic leukemia : MCL

    Magister-uppsats, Mälardalens högskola; Akademin för hälsa, vård och välfärd; Akademin för hållbar samhälls- och teknikutveckling

    Författare :Vasanthakumar Thirugnanam; []
    Nyckelord :;

    Sammanfattning : Mantle cell lymphoma (MCL) is a non-Hodgkin B-cell lymphoma with very bad prognosis. The genetic hallmark of MCL, is the translocation t(11;14)(q13;q32) which leads to overexpression of cyclin D1, a D-type cyclin that is not usually expressed at high levels in normal B lymphocytes. LÄS MER