Sökning: "Maria Khihon Rokhas"

Hittade 1 uppsats innehållade orden Maria Khihon Rokhas.

  1. 1. Development of an assay for screening drug candidates for mechanism-based inhibition of human CYP3A4

    Master-uppsats, Institutionen för livsvetenskaper

    Författare :Maria Khihon Rokhas; [2008]
    Nyckelord :;

    Sammanfattning : Cytochrome P450 (CYP) constitutes a superfamily of heme- containing enzymes that catalyze the oxidative biotransformation of structurally diverse xenobiotics including pharmaceuticals and drugs. Cytochrome P450 3A4 is not only the most abundant isoform in human liver but is also responsible for metabolizing approximately 60% of therapeutic drugs. LÄS MER