Sökning: "Medical chemistry"

Visar resultat 1 - 5 av 28 uppsatser innehållade orden Medical chemistry.

  1. 1. Phenol-Protein Solution Stability

    Magister-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Johan Sjölund; [2022]
    Nyckelord :Phenol; Protein; Proteins; Lysozyme; Betalactoglobulin; Trastuzumab; Lipase; GAZ; GA-Z; Palifermin; Titration; Probedrum; Pharmaceutical Technology; Chemistry;

    Sammanfattning : Phenol is a commonly used preservative in pharmaceutical protein solutions. It is compatible with most proteins but can cause aggregation and denaturation at higher concentrations or in more sensitive proteins. LÄS MER

  3. 2. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Johannes Lidberg; [2022]
    Nyckelord :Physical biochemistry; Fluorescence; In vitro transcription; RNA; Terminal deoxynucleotidyl transferase; Nucleobase analogue; Chemistry;

    Sammanfattning : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. LÄS MER

  4. 3. Synthesis of a rotaxane with switchable lanthanide luminescence

    Master-uppsats, KTH/Organisk kemi

    Författare :Anja Ramström; [2022]
    Nyckelord :mechanically interlocked molecules; supramolecular chemistry; luminescence; rotaxanes; lanthanides; mekaniskt sammankopplade molekyler; supramolekylär kemi; luminescens; rotaxaner; lantanider;

    Sammanfattning : I rotaxaner följs förflyttningen av makrocykeln vanligtvis med 1H-NMR spektroskopi. Målet med detta projekt är i stället att utveckla ett system som möjliggör att förflyttningen av makrocykeln kan observeras med hjälp av luminiscerande lantanid emission. LÄS MER

  5. 4. Surface Functionalization of Nanowires Using Silane-PEG Compounds

    Master-uppsats, Lunds universitet/Centrum för analys och syntes

    Författare :Hedvig Ekfors Elvin; [2022]
    Nyckelord :Functionalization; Nanowires; Silanization; Surface Chemistry; Materials Chemistry; Chemistry;

    Sammanfattning : Introduction: GaP nanowires were functionalized using silane-PEG-NH2 and compared with cellulose acetate, PAcrAm™-g-(PMOXA, amine, silane) and a non-functionalized reference sample. Functionalization would allow strong, covalent anchoring of antibodies instead of adsorption. LÄS MER

  7. 5. Development of a novel quantitative PCR analysis method for HIV-1

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Anna-Malin Hallberg; [2021]
    Nyckelord :HIV; PCR; primers; probes; virus; detection; blood plasma; pathogen; biological pharmaceutical; protein-based pharmaceutical; genotype; subtype; RT qPCR; extraction; TaqMa; RNA virus; cross-dimer; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Sammanfattning : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. LÄS MER