Sökning: "Metabolomics"

Visar resultat 1 - 5 av 19 uppsatser innehållade ordet Metabolomics.

  1. 1. The next-generation of aquatic effect-based monitoring? : A critical review about the application,challenges and barriers with omics in field

    Magister-uppsats, Linnéuniversitetet/Institutionen för biologi och miljö (BOM)

    Författare :Sara Sahlin; [2019]
    Nyckelord :Omics; transcriptomics; proteomics; metabolomics; water monitoring; effect-based;

    Sammanfattning : Traditional water monitoring encounter limitations due to the large number of contaminants present in our waters possible giving raise to mixture effects. This thesis aimed to investigate how the emerging omics approaches (transcriptomics, proteomics and metabolomics) can be used as an effect-based monitoring approach to assess and predict adverse effects in the freshwater environment. LÄS MER

  2. 2. Investigation of the relation between microbiotic changes and Alzheimer's Disease using machine learning on bile acids

    Kandidat-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS); KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Victoria Hedenmalm; Alexander Westberg-Bladh; [2018]
    Nyckelord :Alzheimer s disease; mild cognitive impairment; machine learning; microbiota; gut flora; bile acids; ADNI; classification; metabolomics; Alzheimers sjukdom; mild kognitiv störning; maskininlärning; tarmflora; gallsyra; ADNI; klassificering;

    Sammanfattning : Alzheimer's disease (AD) is an increasing problem in modern society, both with regards to public health and cost of care. The causes of AD are not yet fully understood, and there is no cure or inhibiting drug. LÄS MER

  3. 3. Investigation into the metabolic effect of sarcosine on prostate cancer

    Master-uppsats, SLU/Department of Molecular Sciences

    Författare :Simon Larsson; [2018]
    Nyckelord :prostate cancer; Metabolomics; NMR-spectroscopy; Metabolism; Sarcosine;

    Sammanfattning : Prostate cancer is one of the most common form of human cancer in the world and the most common form of cancer in men in the Western world. There are many molecular factors of prostate cancer, both proteins and metabolites. LÄS MER

  4. 4. Conditioning of chromatographic systems prior to metabolomic studies : Investigation of the conditioning effect and the possibility to alter it

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för analytisk farmaceutisk kemi

    Författare :Jasmin Telo; [2017]
    Nyckelord :Analytical chemistry; metabolomics; metabonomics; conditioning; conditioning effect; UPLC; Q-TOF; HILIC; Protein precipitation; Liquid-liquid extraction;

    Sammanfattning : The conditioning effect in metabolomic studies is the phenomenon of initial variation of analytical results in the first 5-10 injections of a biological sample in chromatographic systems. The deviation manifests itself as a drift in retention time, peak area and in multivariate analysis. LÄS MER

  5. 5. Daggmaskmetabolism: En potentiell bioindikator vid sanering av petroleumförorenad mark - En litteraturstudie

    Kandidat-uppsats, Lunds universitet/Miljövetenskaplig utbildning

    Författare :Martin Larsson; [2017]
    Nyckelord :Earthworm Metabolism 1H-NMR Bioindicator Petroleum Soil; Earth and Environmental Sciences;

    Sammanfattning : Remediating petroleum contaminated soil is a big task. Ex situ methods involve digging up, transporting, remediating and returning contaminated soil which is expensive and environmentally hazardous. Therefore in situ methods of soil remediation are being developed. However, these methods require some form of validation. LÄS MER