Sökning: "Microtubule-associated protein tau"

Hittade 2 uppsatser innehållade orden Microtubule-associated protein tau.

1. 1. Differential Thyroid Hormone Signaling in Human Astrocytes and Microglia

   Uppsats för yrkesexamina på avancerad nivå, Örebro universitet/Institutionen för naturvetenskap och teknik

   Författare :Renée Levisson; [2021]
   Nyckelord :Thyroid hormones; Signaling; Astrocytes; Microglia;

   Sammanfattning : Thyroid hormones (THs) play a fundamental role in brain function during development and adulthood. THs are essential regulators of neurogenesis, cell maturation and migration as well myelination and synaptogenesis. LÄS MER

3. 2. Bacterial Display of a Tau-Binding Affibody Construct:Towards Affinity Maturation

   Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Författare :Moira Ek; [2020]
   Nyckelord :Microtubule-associated protein tau; Neurodegenerative disorders; Alzheimer’s disease; Affibody molecules; Affinity maturation; Staphylococcal surface display; Escherichia coli display; Flow cytometry; Cell sorting;

   Sammanfattning : Aggregation of microtubule-associated protein tau is involved in the pathology of several neurodegenerative diseases, including Alzheimer’s disease. The affibody TP4 has been shown to inhibit this aggregation process, and its target-binding positions were previously grafted onto a dimeric affibody scaffold, creating the sequestrin seqTP4. LÄS MER