Sökning: "Mitochondrial Quality Control"

Hittade 3 uppsatser innehållade orden Mitochondrial Quality Control.

  1. 1. Effect of perfluorononanoic acid (PFNA) on bovine early embryo development in vitro

    Uppsats för yrkesexamina på avancerad nivå, SLU/Dept. of Clinical Sciences

    Författare :Jacklin Kjellgren; [2017]
    Nyckelord :bovine; embryo development; IVF; IVP; perfluorononanoic acid; PFNA; mitochondria; lipid; toxicity;

    Sammanfattning : Perfluoroalkyl and polyfluoroalkyl substances (PFASs) is a large family of highly fluorinated chemicals, used in different commercial products (e.g. in clothing, shampoos, kitchenware and fire-fighting foams) utilizing their different properties, and have been found in wildlife, humans and in the environment. LÄS MER

  3. 2. Identification of Novel Regulators of Mitochondrial Protein Quality Control

    Master-uppsats, Lunds universitet/Tillämpad biokemi

    Författare :My Bratbakken Lundvall; [2015]
    Nyckelord :Mitochondrial Quality Control; Oxidative Stress; Ubiquitin ligases; Ubiquitin; Yeast; Parkinson s Disease; Mitochondria; Paraquat; Oxidative Damage; Superoxides; tillämpad biokemi; applied biochemistry; Technology and Engineering; Chemistry; Biology and Life Sciences;

    Sammanfattning : Chronic pesticide exposure has been linked to several human diseases including cancer, Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, cardiovascular disease, and kidney disease. Due to the potential risks to human health, the usage of pesticides has been a controversial topic. LÄS MER

  4. 3. Elucidation of the role of the MICOS complex in signal transduction from mitocondrial DNA nucleoids

    Master-uppsats, Lunds universitet/Tillämpad biokemi

    Författare :Michael Hellman; [2015]
    Nyckelord :tillämpad biokemi; applied biochemistry; Chemistry; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : The MICOS complex protein MicF has recently been identified to play a vital role in the mitochondrial DNA inheritance checkpoint, a control system that halts cell cycle progression in cells lacking mitochondrial DNA (mtDNA). We show in this report that another member of the complex, MicA, also plays an important role in the mtDNA inheritance checkpoint as its deletion led to cell cycle progression in cells lacking mtDNA (Rho0 cells). LÄS MER