Sökning: "Neuredegenerative diseases"

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  1. 1. Synthesis of proteophenes that can be utilized as fluorescent ligands for biological targets

    Master-uppsats, Linköpings universitet/Kemi

    Författare :Linnea Björk; [2019]
    Nyckelord :Fluorescent probes; Neuredegenerative diseases; Luminescent Conjugated Oligothiophenes; Protein misfolding; Aggregates; Amyloids; Alzheimer’s disease; Aβ-plaque;

    Sammanfattning : Small fluorescent probes are important tools when studying protein aggregates involved in different neurodegenerative diseases, such as Alzheimer’s disease. Luminescent conjugated oligothiophenes have been developed and shown to be excellent ligands when studying morphology among amyloids, due to their conjugated thiophene backbone that provides them with unique photophysical properties. LÄS MER