Sökning: "Neurodegenerative disorders"

Visar resultat 1 - 5 av 19 uppsatser innehållade orden Neurodegenerative disorders.

  1. 1. Structural and Functional Characterisation of the Human Mitochondrial Pyruvate Carrier

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Simon Gripvall; [2023]
    Nyckelord :biochemistry; complex; MPC; proteoliposomes; pyruvate; transport; Chemistry;

    Sammanfattning : The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases. LÄS MER

  3. 2. Neural Correlates of Parkinson’s Disease Motor Symptoms : A pipeline for exploration of correlation between neural and kinematic data

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Evelyn Steinbrück; [2022]
    Nyckelord :Parkinson’s Disease; neural modulation; neurodegenerative disorders; DBS; DCS; closed-loop neural stimulation;

    Sammanfattning : Parkinson’s Disease (PD) is a neurodegenerative disorder, within this categoryof diseases it is among the most prevalent worldwide. The etiology of PD isbased in progressive deterioration of neural tissue in the basal ganglia (neuronalnuclei located at the base of the cerebrum) and their related structures. LÄS MER

  4. 3. Accuracy evaluation of using Graph Theory metrics for functional connectivity analysis MCI classification

    Kandidat-uppsats, KTH/Datavetenskap

    Författare :Pablo Urquijo Martínez; [2022]
    Nyckelord :;

    Sammanfattning : Mild Cognitive Impairment (MCI) is an intermediate stage between the physiological cognitive deterioration due to ageing and a nonphysiological stage of dementia. MCI has morbidity between 12% and 18% of the population aged over 65 [1]. LÄS MER

  5. 4. Lion’s mane mushroom : A fungus to remember, a novel venture into dementia therapy

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Sophia Datsen; [2022]
    Nyckelord :;

    Sammanfattning : As life expectancy increases globally, so does the prevalence of age-related diseases, some of which are more difficult to adapt to and accommodate for than others. In particular, neurodegenerative disorders are among those for which adaptations are more complex, often requiring long-term care. LÄS MER

  7. 5. Analysis of Brain Signals from Patients with Parkinson’s Disease using Self-Supervised Learning

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Emma Lind; [2022]
    Nyckelord :Machine Learning; Self-supervised learning; Feature extraction; Parkinson’s Disease; Magnetoencephalography; Electroencephalogram; Maskininlärning; Självlärande inlärning; Särdragsextraktion; Parkinsons sjukdom; Magnetoencefalografi; Elektroencefalografi;

    Sammanfattning : Parkinson’s disease (PD) is one of the most common neurodegenerative brain disorders, commonly diagnosed and monitored via clinical examinations, which can be imprecise and lead to a delayed or inaccurate diagnosis. Therefore, recent research has focused on finding biomarkers by analyzing brain networks’ neural activity to find abnormalities associated with PD pathology. LÄS MER