Sökning: "Nucleobase analogue"

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  1. 1. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Johannes Lidberg; [2022]
    Nyckelord :Physical biochemistry; Fluorescence; In vitro transcription; RNA; Terminal deoxynucleotidyl transferase; Nucleobase analogue; Chemistry;

    Sammanfattning : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. LÄS MER