Sökning: "Optogenetics"

Visar resultat 1 - 5 av 9 uppsatser innehållade ordet Optogenetics.

  1. 1. Let Us Put Our Brains in the Spotlight – Literally!

    Kandidat-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Elsa Karjalainen; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Neurons are the working force in each vertebrate’s nervous system. These small cells have the important task of transferring information in the form of electrical charges called action potentials. Neurons make it possible for us to sense touch, process our environment, and store memory. LÄS MER

  2. 2. Optogenetic and multiplexed gene editing in primary T-cells.

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Daniel Lake; [2023]
    Nyckelord :T-cells; BLU-VIPR; optogenetics; optogenetic; multiplex; KO; Cre; mice;

    Sammanfattning : Current T-cell tracking techniques in vivo are limited. The ability to successfully target a gene in vivo in T-cells and track movement throughout its life cycle provides an exciting opportunity to elucidate the functions of genes. LÄS MER

  3. 3. Sex-differences in reported adverse side-effects caused by Deep Brain Stimulation therapy in the subthalamic nucleus

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Lucas Werner; [2021]
    Nyckelord :Deep brain stimulation; subthalamic nucleus; sex-differences; STN-DBS; Parkinson s disease;

    Sammanfattning : Parkinson’s disease is a common neurological disease which will progressively damagedopaminergic neurons in the brain. Later stages of the disease will result in death of theneurons. The diagnosis is often made with respect to the motor symptoms, which includetremors, bradykinesia, and rigidity. LÄS MER

  4. 4. Whole-Cell Patch Clamp Investigations on Rapid Synaptic Scaling of Mouse CA1 Pyramidal Neurons under Optogenetic Stimulation

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Leonard Groth; [2021]
    Nyckelord :Patch clamp; Electrophysiology; Optogenetics; Epilepsy; Voltage clamp; Current clamp; Neuroscience; Applied Biochemistry; Tillämpad biokemi; Technology and Engineering;

    Sammanfattning : The brain consists of billions of neurons forming intricate contiguous networks. The connective strength in these networks change throughout life in response to experience and environmental stimuli. LÄS MER

  5. 5. Validation of micro-platelet LED for subcellular optogenetic activation in primary cell cultures

    Master-uppsats, Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

    Författare :Daniel Jaghobi Pourshalmani; [2018]
    Nyckelord :Optogenetics; epilepsy; microplatelet; LED; primary cell cultures; adhesion proteins; electrophysiology; Medicine and Health Sciences;

    Sammanfattning : Epilepsy is to this day still a serious neurological diseases where treatments such as pharmaceutical agents and surgery can at most alleviate the symptoms, but not cure it. This disease is still not fully understood at a cellular and network-level, but the recent advancements in the field of optogenetics can serve as an alternative way of studying the brain and diseases such as epilepsy. LÄS MER