Sökning: "PRC2"

Hittade 2 uppsatser innehållade ordet PRC2.

1. 1. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

   Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Ojong Tabi Ojong Besong; [2021]
   Nyckelord :;

   Sammanfattning : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. LÄS MER

3. 2. Regulation of TGFß signalling by the long noncoding RNA TGFß2-AS1

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Paula Elhorst; [2018]
   Nyckelord :TGFß; signalling; lncRNA; long non-coding RNA; regulation; TGFß2-AS1; cancer; PRC2; Polycomb Repressive Complex; EMT; eptihelial-to-mesenchymal transistion;

   Sammanfattning : Long noncoding RNAs have been shown to regulate many signalling pathways and their expression has been linked to the development of many cancers. Here we assess the involvement of the long noncoding RNA TGFß2-AS1 in the regulation of the TGFß signalling pathway, specifically its involvement in the TGFß induced process of EMT. LÄS MER