Sökning: "PacBio sequencing"

Hittade 3 uppsatser innehållade orden PacBio sequencing.

1. 1. Whole-Genome Sequencing of two Swedish Individuals on PromethION

   Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

   Författare :Nazeefa Fatima; [2019]
   Nyckelord :Biology and Life Sciences;

   Sammanfattning : Background: Chromosomes can undergo various changes such as deletions, inversions, insertions, and/or translocations resulting in structural variation differences between individuals. Structural variants are a common source of variability in the human genome and have been known to be associated with common diseases such as autism, cancer, and rare human diseases [1, 2]. LÄS MER

3. 2. Validation of a new software for detection of resistance associated substitutions in Hepatitis C-virus

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Caitlin Vigetun Haughey; [2019]
   Nyckelord :Hepatitis C virus; HCV; Resistance; NS5A; Resistance associated substitutions; RAS; PacBio sequencing; Bioinformatics; Hepatit C virus; HCV; Resistens; NS5A; Sekvensering; PacBio; Bioinformatik;

   Sammanfattning : Hepatitis C infection is a global disease that causes an estimated 399,000 deaths per year. Treatment has improved dramatically in recent years through the development of direct acting antivirals that target specific regions of the Hepatitis C virus (HCV). LÄS MER

4. 3. Evaluation of de novo assembly using PacBio long reads

   Magister-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Huiwen Che; [2016]
   Nyckelord :;

   Sammanfattning : New sequencing technologies show promise for the construction of complete and accurate genome sequences, by a process called de novo assembly that joins reads by overlap to longer contiguous sequences without the need for a reference genome. High-quality de novo assembly leads to better understanding in genetic variations. LÄS MER