Sökning: "PfDHODH"

Hittade 2 uppsatser innehållade ordet PfDHODH.

  1. 1. Synthesis of novel PfDHODH inhibitors based on 4-aminocoumarin structures

    L3-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Federico Valerio; [2016]
    Nyckelord :PfDHODH; coumarins; synthesis; medicinal chemistry; inhibitors; Malaria; organic chemistry; organisk kemi; Chemistry;

    Sammanfattning : Malaria is an infectious disease caused by the protozoan of the genus Plasmodium. It is a major problem in third-world countries, with hundreds of millions of infections and millions of fatalities annually. The extreme challenge in malaria management is the resistance of parasites to traditional chemotherapies like chloroquine and artemisinin. LÄS MER

  3. 2. Investigation of novel malaria parasite enzyme (DHODH) inhibitors based on 4-amino-3-benzylcoumarin and 4-amino-8-azacoumarin scaffolds

    L3-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Iacopo Galleano; [2013]
    Nyckelord :organisk kemi; Organic Chemistry; Chemistry;

    Sammanfattning : Popular summery Malaria is a parasitic disease caused by five species of the genus Plasmodium (P. falciparum, P. vivax, P. ovale, P. LÄS MER