Sökning: "Phosphorylation"

Visar resultat 1 - 5 av 49 uppsatser innehållade ordet Phosphorylation.

  1. 1. Metabolic Crisis Induced by Antiepileptic Drugs in Patients with Mitochondrial Epilepsy : The Effect of Valproic Acid, Topiramate and Propofol on Mitochondrial Function

    Kandidat-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Angelica Dahlgren; [2023]
    Nyckelord :ATP; epilepsy; mitochondria; oxygen consumption; propofol; topiramate; valproic acid;

    Sammanfattning : Mitochondria are important cytosolic organelles present in nearly all eukaryotic cells. The main function of mitochondria are to generate the vast majority of ATP through the process of oxidative phosphorylation. LÄS MER

  3. 2. Effects of phosphorylation on the ADP-ribosylation activity of PARP16

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Virginia Martín Cristóbal; [2023]
    Nyckelord :ADP-ribosylation; Kinases; PARP16; Phosphorylation; UPR biochemistry; Biochemistry; Chemistry;

    Sammanfattning : PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. LÄS MER

  4. 3. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Alexandra Johannesson; [2023]
    Nyckelord :neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Sammanfattning : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. LÄS MER

  5. 4. Ligand-stimulated cleavage of PDGFR-beta

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Agni Karolina Tsiatsiou; [2023]
    Nyckelord :;

    Sammanfattning : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. LÄS MER

  7. 5. Serum TK1 activity and SAA concentration as biomarkers to differentiate lymphoma from gastrointestinal disease in cats

    Master-uppsats, SLU/Dept. of Clinical Sciences

    Författare :Amanda Friman; [2023]
    Nyckelord :lymphoma; gastrointestinal lymphoma; feline lymphoma; inflammatory bowel disease; IBD; thymidine kinase 1; TK1; biomarker; cancer; cats;

    Sammanfattning : Alimentary lymphoma is one of the most common malignant neoplasms in the gastrointestinal (GI) tract in cats. Since the clinical signs often are identical to those of inflammatory bowel disease (IBD), and the findings on diagnostic imaging and endoscopic mucosal biopsies overlap, invasive biopsy sampling from the GI tract is needed to be able to differentiate these two diseases from each other. LÄS MER