Sökning: "Phosphorylation"

Visar resultat 1 - 5 av 36 uppsatser innehållade ordet Phosphorylation.

  1. 1. Development of an improved psilocybin synthesis

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Uppsala universitet Innovation (UU Innovation)Uppsala universitet/Läkemedelsdesign och läkemedelsutveckling

    Författare :Reham Shaba; [2020]
    Nyckelord :;

    Sammanfattning : Psilocybin is a hallucinogenic compound found in fungi and is currently evaluated inclinical trials for treatment of depression, anxiety and addiction. Psilocybin is aprodrug of the pharmacologically active metabolite, psilocin. LÄS MER

  3. 2. The role of salt inducible kinases in the regulation of the mammalian target of rapamycin pathway in adipocytes

    Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Sulochana Kotresh Jali; [2020]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Salt inducible kinase 2 (SIK2) is found abundantly in adipose tissue and may have a role in the development of diabetes. SIK2 is downregulated in insulin-resistant and obese individuals, thereby providing a new potential target for therapeutic solutions. LÄS MER

  4. 3. Epigenetic Regulation of Mitochondrial DNA

    Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Jennie Johansson; [2020]
    Nyckelord :Acetylation; Epigenetics; Heteroplasmy; Methylation; Mitochondrial haplotype; Mitochondrion; Non coding RNA; Phosphorylation;

    Sammanfattning : This mini-review investigates and compiles the latest knowledge regarding epigenetic changes on the mammalian mitochondrial DNA and its proteins. Methylation of the DNA, acetylation of the proteins and silencing of genes by short non-coding RNAs are the main epigenetic changes known today to affect mitochondrial DNA, mostly leading to repression. LÄS MER

  5. 4. Histone modifications and their role in splicing

    Kandidat-uppsats, Linköpings universitet/Biologi

    Författare :Anna Wettermark; [2020]
    Nyckelord :Splicing; Spliceosome; Histone modifications; epigenetics; histone methylation; histone acetylation; histone phosphorylation; histone ubiquitination;

    Sammanfattning : Splicing is the process when introns gets removed and exons are spliced together. This is an important step to form a clean mRNA with no unnecessary sequences that could interrupt protein synthesis. There are different types of splicing and some of them need a complex called spliceosome. LÄS MER

  7. 5. Varför binder dasatinib mycket bra till vissa proteiner men mindre bra till andra?

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Mohammad Kher Ataya; [2020]
    Nyckelord :;

    Sammanfattning : Introduction: Cancer is a group of about 200 different types of diseases. Cancer can appear in different cells and tissues in the body when abnormal cells grow in an uncontrolled manner and invade other tissues. A multistep process that occurs over a long period eventually leads to the onset of cancer. LÄS MER