Sökning: "Phosphorylation"

Visar resultat 11 - 15 av 49 uppsatser innehållade ordet Phosphorylation.

  1. 11. Investigating Minor States of the Oncoprotein N-MYC, with Focus on Proline Cis/Trans Isomerisation using NMR Spectroscopy

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Frida Haugskott; [2021]
    Nyckelord :Myc; N-Myc; Intrinsically Disordered protein IDP ; Proline; cis-trans isomerisation; minor conformation; NMR; cancer;

    Sammanfattning : MYC is a family of three regulator genes that codes for transcription factors. Expression of Myc proteins from MYC genes is found to be deregulated in 70 % of all cancer forms. The three human homologs C-Myc, N-Myc and L-Myc are mainly associated with cancer in the lymphatic system, nerve tissues and lung cancer, respectively. LÄS MER

  3. 12. Evaluation of the impact of mitochondrial variation in the estimation of breeding values for dairy cattle

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Gabriela Mafra Fortuna; [2021]
    Nyckelord :mitogenome; variance components; milk yield; simulation;

    Sammanfattning : Mitochondria are independent cellular components responsible for cellular respiration. Through oxidative phosphorylation they convert Adenosine diphosphate and inorganic phosphate into Adenosine Triphosphate, ATP, the essential molecule sourced by all intracellular metabolic processes. LÄS MER

  4. 13. Molecular mechanisms underlying platelet inhibition obtained by novel piperazine-purine analogues

    Kandidat-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Josef Jakobsson; [2021]
    Nyckelord :;

    Sammanfattning : Introduction. MK-substances are a new class of piperazine-purine analogues bearing nitrate esters with confirmed cardioprotective, anti-inflammatory and antithrombotic effects. LÄS MER

  5. 14. Development of an improved psilocybin synthesis

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Uppsala universitet Innovation (UU Innovation); Uppsala universitet/Läkemedelsdesign och läkemedelsutveckling

    Författare :Reham Shaba; [2020]
    Nyckelord :;

    Sammanfattning : Psilocybin is a hallucinogenic compound found in fungi and is currently evaluated inclinical trials for treatment of depression, anxiety and addiction. Psilocybin is aprodrug of the pharmacologically active metabolite, psilocin. LÄS MER

  7. 15. The role of salt inducible kinases in the regulation of the mammalian target of rapamycin pathway in adipocytes

    Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Sulochana Kotresh Jali; [2020]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Salt inducible kinase 2 (SIK2) is found abundantly in adipose tissue and may have a role in the development of diabetes. SIK2 is downregulated in insulin-resistant and obese individuals, thereby providing a new potential target for therapeutic solutions. LÄS MER