Sökning: "Protein network"

Visar resultat 1 - 5 av 65 uppsatser innehållade orden Protein network.

1. 1. Randomized Diagonal Estimation

   Master-uppsats, KTH/Matematik (Avd.)

   Författare :Niclas Joshua Popp; [2023]
   Nyckelord :Diagonal estimation; randomized numerical linear algebra; low-rank approximation; matrix functions; Diagonalestimering; randomiserad numerisk linjär algebra; lågrankad approximation; matrisfunktioner;

   Sammanfattning : Implicit diagonal estimation is a long-standing problem that is concerned with approximating the diagonal of a matrix that can only be accessed through matrix-vector products. It is of interest in various fields of application, such as network science, material science and machine learning. LÄS MER

3. 2. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Beräkningsbiologi och bioinformatik

   Författare :Linde Brokmar; [2023]
   Nyckelord :Protein design; de novo design; protein engineering; generative ai; machine learning; peptide binders; AF2; EvoBind; RFdiffusion; ProteinMPNN;

   Sammanfattning : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. LÄS MER

4. 3. Addition of PromOat Beta-Glucan and Guar-gum to Gluten- Free Wheat Starch Pan Bread to increase Fiber while maintaining the Quality in Texture

   Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

   Författare :Devika Singh; [2023]
   Nyckelord :Gluten-Free bread; PromOat; Guar-Gum; Food technology; Technology and Engineering;

   Sammanfattning : Gluten-free products have gained great attention in the last few years due to the growing incidence of celiac disease and the intolerance to gluten. The project is aimed to investigate the effects of adding PromOat, a good source of B-glucan to increase the fiber content and Guar-Gum to overcome the textural deformities in the gluten-free wheat starch Pan bread. LÄS MER

5. 4. Intersecting Graph Representation Learning and Cell Profiling : A Novel Approach to Analyzing Complex Biomedical Data

   Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Nima Chamyani; [2023]
   Nyckelord :Graph representation learning; Cell profiling; Biological systems; Network medicine; Graphs; Machine learning techniques; Graph neural networks GNNs ; Protein-Compound-Pathway interactions; Biomarkers; Drug discovery;

   Sammanfattning : In recent biomedical research, graph representation learning and cell profiling techniques have emerged as transformative tools for analyzing high-dimensional biological data. The integration of these methods, as investigated in this study, has facilitated an enhanced understanding of complex biological systems, consequently improving drug discovery. LÄS MER

7. 5. Gene Biomarker Identification by Distinguishing Between Small-Cell and Non-Small Cell Lung Cancer Through a Module-Based Approach

   Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Noor Haval Jamal; [2023]
   Nyckelord :;

   Sammanfattning : Lung cancer is the leading cause of cancer-related deaths worldwide and is divided into two broad histological types, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Network module-based approach is applied to lung cancer subtypes in order to analyze and compare the results with previous literature and thus discover new genetic biomarkers and/or confirm previously discovered ones. LÄS MER