Sökning: "Regulatory gene network"

Visar resultat 6 - 10 av 23 uppsatser innehållade orden Regulatory gene network.

1. 6. Energy Landscapes for Early T Cell Development

   Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

   Författare :Yukun Cheng; [2022]
   Nyckelord :Physics and Astronomy;

   Sammanfattning : T cell lineage development from an early thymic progenitor involves programmed shutoff of progenitor gene expression, upregulation of T cell specification genes, and proliferation. This biological system has been deeply studied and a gene regulatory network (GRN) that can accurately describe the system has been presented. LÄS MER

3. 7. Imputing connections of random gene networks from time series data using ANNs

   Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

   Författare :Sofia Andersson; [2022]
   Nyckelord :artificial neural networks; ANNs; gene regulatory networks; GRNs; imputation; gene regulatory network imputation; GRN imputation; CNNs; convolutional neural network; randomly generated networks; ternary classification; binary classification; network inference; Physics and Astronomy;

   Sammanfattning : This thesis presents the architecture of a convolutional neural network which is trained to impute the connections of randomly generated gene regulatory networks under varying amounts of regularisation. The generated gene networks are simulated from 10 different starting conditions for each set of connections in order to obtain multiple time series. LÄS MER

4. 8. Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

   Magister-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

   Författare :Fredrik Bertilsson; [2022]
   Nyckelord :Biophysics; systems biology; gene regulatory networks; neural tube; isthmic organizer; midbrain-hindbrain boundary; WNT; FGF; morphogens; reaction-diffusion; finite-difference; 3D modelling; Physics and Astronomy;

   Sammanfattning : Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. LÄS MER

5. 9. Investigation of the role of RNA-binding proteins in bacterial gene regulation

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Mikrobiologi och immunologi

   Författare :Sophie Baars; [2022]
   Nyckelord :;

   Sammanfattning : Salmonella is a common food-borne, intracellular pathogen that causes infections in animals and humans. During infection of the host, flagella serve as important virulence factors that enable the bacterium to reach the site of infection and adhere to the host-cell. LÄS MER

7. 10. Identification and network analysis of candidate microRNA biomarkers in neuroblastoma : A meta-analysis

   Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Andreas Svensson; [2022]
   Nyckelord :;

   Sammanfattning : Neuroblastoma constitutes roughly 8% of all childhood cancers where 95% of all neuroblastoma cases occur before the age of 10. The survival rate of infants and young children is very poor, which alone contributes to research novel biomarkers for classification methods, improved diagnosis and better anti-tumor therapies. LÄS MER