Sökning: "Rigid helix fusion"

Hittade 1 uppsats innehållade orden Rigid helix fusion.

  1. 1. Design, production and evaluation of cross linked target proteins to an affibody-based carrier framework aimed for affinity protein: antigen structure determination using single particle Cryo-EM

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Richard Brunsell; [2021]
    Nyckelord :Cryo-EM; Structure determination; Protein A; Affibody; Aldolase; Scaffold; Rigid helix fusion; Photoconjugation; UV crosslinking; BPA;

    Sammanfattning : Small proteins are difficult to study at high resolution with single-particle cryo-electron microscopy (cryo-EM). In general, sample properties such as large size (> 80 kDa), symmetry and rigidity are key to utilize this technology. LÄS MER