Sökning: "Single-cell analysis"

Visar resultat 11 - 15 av 46 uppsatser innehållade orden Single-cell analysis.

  1. 11. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Mikrobiologi och immunologi

    Författare :Matilda Maxwell; [2023]
    Nyckelord :Bioinformatics; scRNA-seq; avian; immunology; Seurat; leukocytes; chicken; gallus gallus; 10x genomics; PCA;

    Sammanfattning : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. LÄS MER

  3. 12. Molecular mapping of the HGSOC tumour microenvironment

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Philippine Louail; [2023]
    Nyckelord :Immunology; Ovarian cancer; Multiplex Immunofluorescence; scRNA sequencing; Bioinformatics; Image analysis;

    Sammanfattning : High-grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer, and its heterogeneity poses a challenge for the discovery of reliable diagnostic biomarkers, therapeutic targets, and predicting treatment response, particularly to immunotherapy. The current standard diagnostic and treatment options are inadequate, resulting in late diagnosis and poor prognosis. LÄS MER

  4. 13. Developing an Automated System for Yeast Culture Cultivation and Control using Flow Cytometry

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Sara Magnusson; [2023]
    Nyckelord :Yeast; flow cytometry; applied microbiology; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : Flow cytometry is a versatile tool for monitoring a microbial population at a single-cell level. Multiple parameters can be monitored based on the users’ requirements through the utilization of different dyes, biosensors etc. LÄS MER

  5. 14. Production of filamentous fungal biomass on waste-derived volatile fatty acids for ruminant feed supplementation and it's in vitro digestion analysis

    Master-uppsats, Högskolan i Borås/Akademin för textil, teknik och ekonomi

    Författare :Mohammadali Bouzarjomehr; [2022]
    Nyckelord :VFAs volatile-fatty-acids ; Fungi production; Feed production.; Fermentation processes; Aspergillus oryzae; A. oryzae fungal biomass; Sustainability; Rumen fluids; Evaluation of the digestibility of the produced fungal biomass; TT method analysis; Gas production method; Nylon bag method analysis;

    Sammanfattning : Single cell proteins such as that of edible filamentous fungal biomass are considered as a promising sustainable source of animal feed supplementation. Filamentous fungi can be cultivated on different organic substrates including volatile fatty acids (VFAs) such as acetic, propionic, and butyric acids. LÄS MER

  7. 15. Representation learning for single cell morphological phenotyping

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Andreas Nenner; [2022]
    Nyckelord :Deep learning; Image-based profiling;

    Sammanfattning : Preclinical research for developing new drugs is a long and expensive procedure. Experiments relying on image acquisition and analysis tend to be low throughput and use reporter systems that may influence the studied cells. LÄS MER