Sökning: "Spliceosome"

Hittade 3 uppsatser innehållade ordet Spliceosome.

1. 1. Alternativ Splicing som biomarkör vid systemisk lupus erythematosus

   Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

   Författare :Lina Rehnman; [2022]
   Nyckelord :systemisk lupus erythematosus; SLE; alternativ splicing; transkription;

   Sammanfattning : Characteristics as unknown cause, complicated pathophysiology and a great amount of complexity are describing systemic lupus erythematosus (SLE) more than well. It’s an autoimmune disease that is almost exclusive for women in their reproductive years and are believed to correlate with both genetics and environmental factors. LÄS MER

3. 2. Histone modifications and their role in splicing

   Kandidat-uppsats, Linköpings universitet/Biologi

   Författare :Anna Wettermark; [2020]
   Nyckelord :Splicing; Spliceosome; Histone modifications; epigenetics; histone methylation; histone acetylation; histone phosphorylation; histone ubiquitination;

   Sammanfattning : Splicing is the process when introns gets removed and exons are spliced together. This is an important step to form a clean mRNA with no unnecessary sequences that could interrupt protein synthesis. There are different types of splicing and some of them need a complex called spliceosome. LÄS MER

4. 3. Alternative splicing and its regulation under normal and abnormal conditions

   Kandidat-uppsats, Institutionen för fysik, kemi och biologi

   Författare :Jenny Ackelman; [2010]
   Nyckelord :Alternative splicing; ESE; ESS; hnRNP proteins; ISE; ISS; Regulation; Spliceosome; SR proteins;

   Sammanfattning : During the maturation of pre-mRNA introns are removed and exons are spliced together, to form a primary transcript, a reaction that is catalyzed by the spliceosome. Alternative splicing is a complex reaction that mainly utilizes one of four mechanisms; exon skipping, 5’ splice site choice, 3’ splice site choice and intron retention. LÄS MER