Sökning: "Stepwise Expectation Maximization"
Hittade 2 uppsatser innehållade orden Stepwise Expectation Maximization.
1. Improving the speed and quality of an Adverse Event cluster analysis with Stepwise Expectation Maximization and Community Detection
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för medicinska vetenskaperSammanfattning : Adverse drug reactions are unwanted effects alongside the intended benefit of a drug and might be responsible for 3-7\% of hospitalizations. Finding such reactions is partly done by analysing individual case safety reports (ICSR) of adverse events. The reports consist of categorical terms that describe the event. LÄS MER
2. Individualization of fixed-dose combination regimens : Methodology and application to pediatric tuberculosis
Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskapSammanfattning : Introduction: No Fixed-Dose Combination (FDC) formulations currently exist for pediatric tuberculosis (TB) treatment. Earlier work implemented, in the software NONMEM, a rational method for optimizing design and individualization of pediatric anti-TB FDC formulations based on patient body weight, but issues with parameter estimation, dosage strata heterogeneity and representative pharmacokinetics remained. LÄS MER