Sökning: "Substantia nigra"

Hittade 5 uppsatser innehållade orden Substantia nigra.

1. 1. Non-motor symptoms and their use as markers for prodromal and early Parkinson's disease

   Kandidat-uppsats, Uppsala universitet/Institutionen för organismbiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Aubree Stephens; [2021]
   Nyckelord :Neurology; Parkinson s; non-motor symptom; prodromal;

   Sammanfattning : Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. It is a disease with a broad spectrum of symptoms, both motor and non-motor, but is often only diagnosed when the motor symptoms begin to appear. LÄS MER

3. 2. The subthalamic nucleus in health and disease

   Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Yu Zhang; [2020]
   Nyckelord :;

   Sammanfattning : Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world. PD is caused by degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNc). LÄS MER

4. 3. Optimization of PCR protocols used for genotyping transgenic mice & Evaluation of a method for co-detecting mRNA and protein

   Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Jämförande fysiologi

   Författare :Amanda Isaksson; [2017]
   Nyckelord :Ventral tegmental area; Substantia nigra; Parkinson’s disease; transgenic mice; Cre-Lox recombination;

   Sammanfattning : The aim of the current study was divided into two separate goals, (i) optimization of a number of PCR-based protocols employed for genotyping transgenic mouse lines and (ii) evaluating a protocol for co-detection of mRNA and its correlated protein in the mouse midbrain. The optimization was performed on PCR protocols for genotyping the following transgenic mouse lines; Dat-Cre, Vglut2-Lox, Vglut2-Cre and Vmat2-Lox. LÄS MER

5. 4. Identification and characterization of genes that are involved in reward mechanisms in ethanol self-administration

   L3-uppsats, SLU/Dept. Of Plant Biology

   Författare :Hung Trinh; [2009]
   Nyckelord :brain reward pathway; ethanol self-administration; neurotransmitter receptor; real-time PCR; mRNA; VTA; NAc; Sn; CPu;

   Sammanfattning : Alcohol addiction is one of the most common drug addictions amongst societies. Alcohol abuse, can lead serious injuries, severe diseases or even death. Despite intensive research, complete knowledge about alcohol addiction and a specific "ethanol receptor" has not been found yet. LÄS MER

7. 5. Effects of glial cell line-derived neurotrophic factor (GDNF) on mouse fetal ventral mesencephalic tissue

   Magister-uppsats, Institutionen för biologi och kemiteknik

   Författare :Nina Nevalainen; [2008]
   Nyckelord :Parkinson s disease; dopamine; glial cell line-derived neurotrophic factor GDNF ; ventral mesencephalon; astrocytes;

   Sammanfattning : The symptoms of Parkinson's disease occur due to degeneration of dopamine neurons in substantia nigra. It has been demonstrated that glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor when it comes to protect and enhance survival of dopamine neurons in animal models of Parkinson's disease. LÄS MER