Sökning: "T-cell"

Visar resultat 1 - 5 av 57 uppsatser innehållade ordet T-cell.

  1. 1. Developing a protocol for 3D-printable bioink from decellularised porcine tissue

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Vendela Sandin; [2024]
    Nyckelord :Scaffold; Extracellular matrix; ECM; Bioink; Bioprinting; Collagen; Pharmaceutical technology; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : T-cell administration via a scaffold is a promising tool for treatment of inoperable solid tumours. Traditional scaffold materials lack the complexity of the extracellular matrix (ECM) that cells normally grow in. An alternative is to instead use decellularised ECM (dECM) from biological tissue to create the scaffold. LÄS MER

  3. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Samuel Eriksson Lidbrink; [2023]
    Nyckelord :AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Sammanfattning : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. LÄS MER

  4. 3. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Emilie Allentoft Schousboe; [2023]
    Nyckelord :3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

    Sammanfattning : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. LÄS MER

  5. 4. Optogenetic and multiplexed gene editing in primary T-cells.

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Daniel Lake; [2023]
    Nyckelord :T-cells; BLU-VIPR; optogenetics; optogenetic; multiplex; KO; Cre; mice;

    Sammanfattning : Current T-cell tracking techniques in vivo are limited. The ability to successfully target a gene in vivo in T-cells and track movement throughout its life cycle provides an exciting opportunity to elucidate the functions of genes. LÄS MER

  7. 5. In vitro T cell assays to test CAR T-cell activation in colorectal cancer

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Sara Chavoshlu; [2023]
    Nyckelord :;

    Sammanfattning : .... LÄS MER