Sökning: "TF FVIIa"

Hittade 1 uppsats innehållade orden TF FVIIa.

  1. 1. Characterization of a novel EPHB2 R155C mutant with respect to its proteolytic cleavage by TF/FVIIa

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Ece Akcan; [2021]
    Nyckelord :cancer; colorectal cancer; CRC; ephrin receptor; EPHB2; tissue factor; TF; TF FVIIa; cleavage; cell repulsion;

    Sammanfattning : EPHB2, an ephrin receptor (EPH) from receptor tyrosine kinase (RTK) family, is one of the substrates for tissue factor (TF) - coagulation factor VIIa (FVIIa) complex and it is cleaved in its ectodomain. EPHB2 cleavage is important for ephrin receptor (EPH) - ephrin ligand (EFN) signaling and cell repulsion. LÄS MER