Sökning: "Therapeutics"
Visar resultat 1 - 5 av 51 uppsatser innehållade ordet Therapeutics.
1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemiSammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER
2. Establishing novel approaches for assessing safety of genome-editing-based therapeutics
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Genome editing based medicines are a new therapeutic modality being developed. They show great promise for a spectrum of genetic diseases lacking conventional treatment strategies. A major obstacle that prevents such therapies to reach the clinic is their safety. LÄS MER
3. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Beräkningsbiologi och bioinformatikSammanfattning : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. LÄS MER
4. Generation of a new ADAPT library for stability improvement
Master-uppsats, KTH/ProteinvetenskapSammanfattning : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. LÄS MER
5. Exploring the Potential of Camelid Single-Domain Antibodies : Structure, Properties and Diverse Applications in Therapeutics and Diagnostics
Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : .... LÄS MER