Sökning: "Therese Koivula"

Hittade 2 uppsatser innehållade orden Therese Koivula.

1. 1. Production and characterisation of a chlamydial antigen candidate for vaccine trials

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Molekylär biomimetik

   Författare :Therese Koivula; [2021]
   Nyckelord :Chlamydia trachomatis; Immunology; Vaccine; Optimizing protein expression in E. coli; Optimizing protein purification; IMAC; His-tag cleavage; Buffer exchange; Chlamydial antigen;

   Sammanfattning : The bacterium Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infection worldwide. When left untreated, chlamydial infections can lead to severe complications, such as infertility. LÄS MER

3. 2. Drugs of the Future - Bispecific Antibodies : An investigaion of future development needs

   Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Carl Fabian Svahn; Anisha Khan; Amanda Wahlsten; Terese Larsson; Therese Koivula; Thomas Andersson; [2019]
   Nyckelord :bispecific; antibodies; antibody; production; preclinical; clinical; development; knob-into-hole; Duetmab; crossmab; beat; orthogonal; fab;

   Sammanfattning : This report reviews the field of bispecific antibodies, artificially engineered antibodies thathave the ability to bind two or more different antigen simultaneously. Historical as well asrecently developed techniques are demonstrated, together with formats in preclinical andclinical development. LÄS MER