Sökning: "Type I interferon"

Visar resultat 1 - 5 av 12 uppsatser innehållade orden Type I interferon.

  1. 1. Role of androgen receptor signaling in the activation and differentiation of plasmacytoid dendritic cells

    Master-uppsats, Göteborgs universitet / Institutionen för biologi och miljövetenskap

    Författare :Faiza Tahsin Rashid; [2023-06-27]
    Nyckelord :;

    Sammanfattning : Androgens are steroid hormones essential for the development and maintenance of male reproductive organs and secondary sexual characteristics. Plasmacytoid dendritic cells (pDCs) are immune cells that act as the first line of defense against viral infections. LÄS MER

  3. 2. Characterizing the immunogenic cell death induced by Semliki Forest Virus in glioblastoma cell lines

    Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Aishwarya Sivaramakrishnan; [2021]
    Nyckelord :Glioblastoma; Immunogenic Cell Death; Oncolytic Viruses; Semliki Forest Virus; Aishwarya Sivaramakrishnan;

    Sammanfattning : Glioblastoma is the most common primary brain tumor in humans and has a poor prognosis. Current therapies are not curative. Oncolytic viruses (OVs) are being investigated as tools to induce immunogenic cell death (ICD), cell death capable of activating the immune system. LÄS MER

  4. 3. Analysing gene expression of IFN-ɑ stimulated genes in patients with SLE using direct and indirect methods

    Kandidat-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Linn Israelsson; [2021]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system is attacking the body and its tissues. This leads to a chronic inflammation that can affect different parts of the body and therefore present itself in a vast variety of symptoms. LÄS MER

  5. 4. Behandling av kronisk myeloisk leukemi med tyrosinkinasinhibitorer i samband med graviditet

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Fatima Muhson; [2019]
    Nyckelord :TKI; tyrosinkinashämmare; KML; imatinib; nilotinib; dasatanib; bosutinib; ponatinib;

    Sammanfattning : Bakgrund: Vid kronisk myeolid leukemi (KML) överproducerar blodstamceller omogna granulocyter som kan öka risken för infektioner, anemi och lätta blödningar. Ifall sjukdomen inte åtgärdas i tidigt skede så kan cancercellerna konkrurera ut friska blodceller vilket kan leda till ett livshotande tillstånd. LÄS MER

  7. 5. Comparison of the immunomodulatory capabilities of the V and C proteins of different morbilliviruses

    Master-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Nelman Pushpa D Ranasinghe Atapattu Mudiyanselage; [2018]
    Nyckelord :Feline morbillivirus; Canine distemper morbillivirus; Measles morbillivirus; Type I interferon; C protein; V protein;

    Sammanfattning : During a viral infection, when the virus enters into the cytoplasm, different cell types are able to produce interferons (IFN) as a result of interaction between intracellular pattern recognition receptors (PRR) and RNA helicases. This interferon activates and establishes an antiviral state which limits further spread of the virus. LÄS MER