Sökning: "albumin"

Visar resultat 21 - 25 av 85 uppsatser innehållade ordet albumin.

  1. 21. Permeability of fluorescently labelled proteins in silk-based skin equivalent

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Gabriel Chumpitaz Chavez; [2021]
    Nyckelord :skin equivalent; recombinant spider silk; fibroblasts; keratinocytes; permeability; Franz cells; fluorescence; bovine serum albumin; sodium fluorescein salt;

    Sammanfattning : Development of methods for studying drug delivery systems is of great significance for the improvement of topical formulations. Active compounds for topical drug delivery are often formulated into gels and creams, that can be applied onto skin surfaces. LÄS MER

  3. 22. Production and Evaluation of a Bombesin Analogue Conjugated to the Albumin-Binding Domain and DOTA for Prostate Cancer Radiotherapy

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Fredrika Landmark; [2021]
    Nyckelord :bombesin; prostate cancer; radiotherapy; human serum albumin; half-life extension; bombesin; prostatacancer; radioterapi; humant serumalbumin; halveringstidsförlängning;

    Sammanfattning : Prostate cancer is one of the most common types of cancer worldwide and claims hundreds of thousands of lives annually. Currently the most common treatment for prostate cancer is external beam radiotherapy, however, this treatment comes with serious side effects since it lacks selectivity for the cancer cells. LÄS MER

  4. 23. Investigation of possible improvements of the stability of bispecific ADAPT proteins

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Ella Eriksson; [2021]
    Nyckelord :Protein purification; Affinity chromatography; ABD-derived domain; ADAPT protein; simultan binding;

    Sammanfattning : The aim of the project was to identify positions and amino acids that contribute to improved structure and stability of bispecific ADAPT proteins. During the 20 weeks project period, different amino acid substitutions were analysed to evaluate the effect on the three-helical structure and stability of bispecific ADAPTs targeting human serum albumin (HSA) and tumor necrosis factor α (TNFα). LÄS MER

  5. 24. Preanalytisk påverkan av dubbelcentrifugering på rutinkemiska analyser

    Kandidat-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Gustav Forsner; [2020]
    Nyckelord :;

    Sammanfattning : Bakgrund Rör för rutinkemiska analyser centrifugeras i primärvården innan de skickas till USÖ, Universitetssjukhuset Örebro, för analysering. Den gamla sanningen är att rör inte får centrifugeras två gånger och därför behandlas dessa separat från övriga rör på USÖ vilka annars hanteras av automationen som centrifugerar rören före analys. LÄS MER

  7. 25. Method development of an in vitro vertical Franz diffusion cell system to assess permeation of cosmetic active ingredients

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för kemi - Ångström

    Författare :Johanna Mattiasson; [2020]
    Nyckelord :chemistry; method development; Upsalite; Disruptive Materials; Franz; diffusion; penetration; permeation; skin; pharmaceuticals; cosmeceuticals; skincare; cosmetics; actives; mesoporous; material chemistry; kemi; kosmetika; Upsalite; Disruptive Materials; Franzcell; diffusion; läkemedel; metodutveckling; hud; penetration;

    Sammanfattning : For evaluation of potential skincare ingredients, an in-house method using Static Franz diffusion cells and dialysis membranes was developed. Benzoic acid was chosen as a model substance along with L-ascorbic acid and α-Tocopherol. The cell conditions were tailored to encourage transmembrane diffusion. LÄS MER