Sökning: "amyloid fibrils"

Visar resultat 1 - 5 av 21 uppsatser innehållade orden amyloid fibrils.

  1. 1. Can Feeding Amyloid Fibrils Trigger Amyloid Formation in C. Elegans?

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Katarina Norrby; [2023]
    Nyckelord :Amyloid; AA amyloid; Amyloidosis; AA amyloidosis; C. Elegans;

    Sammanfattning : Amyloidosis are diseases caused by misfolded proteins that have transformed into extracellular insoluble amyloid fibrils. One type of amyloidosis is AA amyloidosis caused by AA amyloid and diseases connected are Rheumatoid arthritis and Tuberculosis. C. Elegans is a nematode used as a model organism and in this experiment. LÄS MER

  3. 2. Feasibility of quantitative 99mTc-DPD scintigraphy SPECT/CT for assessing the burden of ATTR cardiac amyloidosis

    Master-uppsats, Umeå universitet/Radiofysik

    Författare :Sajad Kadhim Khalaf; [2023]
    Nyckelord :QSPECT; Amyloidosis; ATTR; LVMI; Recovery Coefficient; SUV; Calibration;

    Sammanfattning : Background: Amyloid transthyretin (ATTR) cardiomyopathy is caused by the deposition of misfolded proteins, known as amyloid fibrils, in the myocardium. Quantitative Single Photon Emission Computed Tomography (QSPECT) utilizing 99mTc-DPD scintigraphy has the potential to assess ATTR-suspected cardiac amyloidosis (CA). LÄS MER

  4. 3. The GSK-3 inhibitor has no effect on production of IL-1β in LPS- and Nigericin-stimulated THP-1 macrophages

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Jessica Halan Söderberg; [2022]
    Nyckelord :;

    Sammanfattning : Inflammation is the body's natural defense reaction and is known since ancient times. The inflammation is divided into two main phases, acute and chronic inflammation dependent on the process and cellular mechanisms of the inflammation. LÄS MER

  5. 4. Study of fibrillation processes of amyloid-like β-lactoglobulin protein

    Master-uppsats, KTH/Kemi

    Författare :Jose Nixon; [2021]
    Nyckelord :bLG; Thioflavin-T Fluroscence; Fibrillation; bLG; Thioflavin-T fluroscens; fibrillering;

    Sammanfattning : Bovint β-laktoglobulinprotein (bLG) är ett litet globulärt protein med 162 aminosyrarester, som vanligtvis finns i mjölkvassle. Under sura förhällanden dissocierar dessa dimera proteiner och bildar amyloidliknande fibriller. LÄS MER

  7. 5. Fluorescent molecules as probes for characterization of amyloid β fibrils

    Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Denisse Marginean; Ebba Hellstrand; [2021]
    Nyckelord :Alzheimer s disease; amyloid beta; amyloid; fluorescent probes; fluorescent ligands;

    Sammanfattning : Alzheimer’s Disease (AD) is the leading cause of dementia in the world and the World Health Organization has recognized AD as a global public health priority. One of the pathological hallmarks of AD is amyloid plaques formed from amyloid β (Aβ) fibrils. Aβ is formed when amyloid precursor protein is cleaved by secretase enzymes. LÄS MER