Sökning: "antibody validation"

Visar resultat 1 - 5 av 10 uppsatser innehållade orden antibody validation.

  1. 1. Single-cell transcriptomic and antibody-based proteomic analysis of Sertoli cell-specific markers in human testis

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Katharina Stanzel; [2023]
    Nyckelord :;

    Sammanfattning : The testis is a complex organ responsible for sperm production and hormone synthesis. Spermatogenesis, the process of sperm formation, occurs in the seminiferous tubules and involves the coordinated development of germ cells with the support of Sertoli cells. LÄS MER

  3. 2. Validation of Treponema pallidum haemoagglutination test compared with Treponema pallidum particle agglutination test

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Emilia Lind; [2023]
    Nyckelord :TP-PA; TP-HA; syphilis; treponemal antibody test; nontreponemal antibody test;

    Sammanfattning : Treponema pallidum (T. pallidum) is the bacteria that causes syphilis, which is a sexually transmitted disease that might give the carrier a multisystemic infection. A combination of serological tests is needed to put a diagnosis of T. pallidum infection, because the bacteria cannot be cultured in vitro. LÄS MER

  4. 3. VISUALIZING CATESTATIN AND CHROMOGRANIN A : An Antibody Validation

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Johan William-Olsson; [2022]
    Nyckelord :Diabetes; immunology; western blot; flow cytometry; immunofluorescence;

    Sammanfattning : Chromogranin A (CgA) and its cleavage product Catestatin (CST) are two very interesting proteins, especially due to their possible involvement in the development of type 1 diabetes. There are currently only a few primary antibodies against CgA and CST, and the ones that do exist are often only recommended for use on one method. LÄS MER

  5. 4. Validation of anti-cytokeratin antibodies used in rapid cancer diagnostics by isoelectric focusing and QCM technology

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Biokemi

    Författare :Reneh Kostines; [2021]
    Nyckelord :IEF; Isoelectric focusing; QCM; Attana; Cytokeratin; Keratin; Attana; Anti-cytokeratin; cancer; UBC; IDL; epithelial carcinomas; Antibody validation; Biosensor; Biosensors;

    Sammanfattning : Antibodies are Y-shaped proteins. In the human body, antibodies areproduced by plasma cells, mainly T and B cells which are included inthe adaptive immune system. The production of antibodies is stimulatedby antigens. The binding between an antigen-specific antibody and itsantigen can be like the interconnect between a lock and a key. LÄS MER

  7. 5. Validering av Dako Omnis Ready-to-Use-antikroppar vid rutinfärgning av Mismatch repair generna MLH1, MSH2, MSH6 och PMS2 vid immunohistokemisk cancerdiagnostik

    Uppsats för yrkesexamina på grundnivå, Örebro universitet/Institutionen för hälsovetenskaper

    Författare :Sofia Källhagen; [2021]
    Nyckelord :Lynch syndrome; colorectal cancer; mismatch repair; immunohistochemistry; antibody; Lynch syndrom; colorektalcancer; mismatch repair; immunohistokemi; antikropp;

    Sammanfattning : Vid cancerdiagnostisering av Lynch syndrom används immunohistokemisk färgning för undersökning av eventuell defekt hos mismatch repair-generna MLH1, MSH2, MSH6 och PMS2. Färgningen använder sig av antikroppar som undersöker om cellkärnor i vävnad har intakta eller förlorade proteinuttryck hos respektive gen. LÄS MER