Sökning: "autophagy"

Visar resultat 1 - 5 av 12 uppsatser innehållade ordet autophagy.

  1. 1. Autophagy and senescence in primary human bronchial epithelial cells in the context of COPD

    Master-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Annie Vegraeus; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD) is the third largest cause of death worldwide, with its most prominent risk factor being inhalation of smoke and pollutants. In this project, we studied two processes that are involved in COPD: autophagy and cellular senescence. LÄS MER

  3. 2. Experimental validation of PLAC8 in small intestinal neuroendocrine tumors

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Martin Nilsson; [2023]
    Nyckelord :;

    Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) are the most common malignant tumor in the small bowel. It is a small-growing cancer with good overall survival 5 years after diagnosis, but no full cure is available when in the metastatic stage. LÄS MER

  4. 3. Intermittent fasting’s impact on autophagy, insulin sensitivity and cortisol in a clinical setting : A Systematic Review

    Kandidat-uppsats, Högskolan i Halmstad/Akademin för företagande, innovation och hållbarhet

    Författare :Marcus Otter; Anton Laag; [2022]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Crystallization, optimization, and crystal structure determination of ligands in complex with galectin-8N

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :George Larsson; [2022]
    Nyckelord :Biochemistry; Structural Biochemistry; Galectin-8; Protein Crystallization; Chemistry;

    Sammanfattning : This thesis focuses on the protein “galectin-8N” which is a lectin protein that takes part in several physiological functions such as inflammation, autophagy, cell migration, and more. The project has three objectives: to observe and increase the reproducibility of crystallization of two variants (wildtype and mutant) of the human protein galectin-8N and to analyze the binding site when three different novel ligands are each inserted. LÄS MER

  7. 5. The roles of heparan sulfate in autophagy

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Asifa Khan; [2022]
    Nyckelord :Heparan sulfate; LC3-II; p62; Autophagy;

    Sammanfattning : Background: Autophagy is a lysosomal degradation process to eliminate damaged components from the cells. It also provides a survival mechanism in stressed conditions and limits growth processes. Heparan sulfate (HS) is a polysaccharide attached to different proteoglycans. LÄS MER