Sökning: "beta cell imaging"

Hittade 4 uppsatser innehållade orden beta cell imaging.

  1. 1. Relation between retinal morphology, visual pathway integrity and plasmatic amyloid beta 42 peptide in old and young beagles

    Master-uppsats, SLU/Dept. of Clinical Sciences

    Författare :Emilia Miranda Peluso; [2020]
    Nyckelord :cognitive dysfunction syndrome; dog; optical coherence tomography; OCT; visual evoked potentials; VEP;

    Sammanfattning : The spontaneously occurring behavioural syndrome referred to as canine cognitive dysfunction (CCD) is considered the canine counterpart of Alzheimer’s disease (AD). Changes in the retina such as nerve fibre layer (NFL) and ganglion cell complex (GCC) thinning have been observed in Alzheimer’s patients. LÄS MER

  3. 2. Modeling of beta-cell Metabolic Activity and Islet Function : a Systems Approach to Type II Diabetes

    Master-uppsats, KTH/Skolan för teknik och hälsa (STH)

    Författare :Fotios Christakopoulos; [2016]
    Nyckelord :cytoskeleton remodelling; particle tracking microrheology; IAPP; type 2 diabetes;

    Sammanfattning : Diabetes has gained growing attendance as one of the key non communicable diseases (NCD) with the World Health Organization identifying it as the focus of the World Health Day 2016. It is reported that more than 420 million people suffer from diabetes, a number predicted to rise in the coming years. LÄS MER

  4. 3. A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT

    Master-uppsats, SLU/Dept. of Clinical Sciences

    Författare :Susanne Andréasson; [2014]
    Nyckelord :Exendin-4; GLP-1R; pig; beta cell imaging; beta cell mass; Exendin-4; gris; betacellsmassan; PET-CT;

    Sammanfattning : Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. LÄS MER

  5. 4. Characterization of the pancreatic β-cell auto antigen targeted by the IC2 monoclonal autoantibody

    Magister-uppsats, Molekylär genetik

    Författare :Md. Golam Kafi Afrose Mia; [2009]
    Nyckelord :Autoantigen; IC2; Beta cell; Biomarker; Diabetes; Monoclonal autoantibody; HPTLC; Immuno TLC; Glycolipids;

    Sammanfattning : IC2, a well known monoclonal autoantibody, derived from newly diabetic BB rat and seems to be an important biomarker for non-invasive functional imaging of beta cells in vivo. It specially and uniquely binds with pancreatic beta cells as confirmed in some previous studies. LÄS MER