Sökning: "bilayer model"

Visar resultat 1 - 5 av 10 uppsatser innehållade orden bilayer model.

  1. 1. Diffusion and Camera-Noise Modelling for Analysis of Single-Particle Tracking Movies

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Erik Clarkson; [2022]
    Nyckelord :reaction-diffusion; camera-noise modelling; single-particle tracking; Gillespie simulations; Physics and Astronomy;

    Sammanfattning : Interactions between T-cells and other body cells is an essential part of the immune system. It involves the binding between surface receptors of the two cells. Specifically, T-cell receptors (TCRs) bind onto pMHC (peptide-loaded major histocompatibility complex) molecules on the partnering cell surface. LÄS MER

  3. 2. In silico and in vitro determination of substrate specificity for Breast Cancer Resistance Protein (BCRP) transporter at the blood-brain barrier

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Fen Wang; [2021]
    Nyckelord :BCRP; substrate specificity; BBB; ATP-binding cassette ABC transporter; Drug transport;

    Sammanfattning : Background The Breast Cancer Resistance Protein (BCRP) drug transporter is important for drug disposition and plays a critical role in regulating drug entry into the brain. Its substrate spectrum overlaps with substrates of Multi Drug Resistance Protein 1 (MDR1, P-gp), which influences and complicates the interpretation of data on drug distribution into tissues (e. LÄS MER

  4. 3. GIANT UNILAMELLAR VESICLES FOR PEPTIDE-MEMBRANE INTERACTION STUDIES USING FLUORESCENCE MICROSCOPY

    Master-uppsats, Linköpings universitet/Biofysik och bioteknik

    Författare :Martin Nilsson; [2020]
    Nyckelord :Giant unilamellar vesicles; Lipid rafts; Fluorescence microscopy; Drug delivery;

    Sammanfattning : Vesicles are a type of biological or biomimetic particle consisting of one or more often spherical bilayers made up of amphipathic molecules, creating a closed system. They can function as an encapsulating device, holding hydrophilic molecules on the inside of the bilayer membrane(s) or hydrophobic molecules in the non-polar interstitial space in the middle of the bilayers. LÄS MER

  5. 4. Constructing supported lipid bilayers from native cell membranes

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Tommy Dam; [2018]
    Nyckelord :T cells; Model membrane systems; Supported lipid bilayers; SLB; biophysical chemistry; biofysikalisk kemi; Chemistry;

    Sammanfattning : The aim of this MSc-project was to investigate whether it is possible to incorporate native cell membrane components from Jurkat T cells into supported lipid bilayers, SLBs, to produce a model membrane system better resembling the native cell membranes in T cells. The procedure of forming native-like SLBs (nSLB) was adapted from an existing protocol and is done through the deposition of hybrid vesicles onto a cleaned glass slide. LÄS MER

  7. 5. Finite Element Analysis of PZT-based Air Flow Sensor

    Master-uppsats, Mittuniversitetet/Avdelningen för elektronikkonstruktion

    Författare :Xie Chuanliang; [2017]
    Nyckelord :Air Velocity; PZT; FEA; COMSOL Multiphysics; Bilayer Cantilever;

    Sammanfattning : This thesis proposes a novel air flow sensor based on PZT material which is used to measure air velocity in an experimental tunnel or indoor ventilation. The work focuses on designing and verifying the sensor model through finite element analysis (FEA) simulation using COMSOL Multiphysics software. LÄS MER