Sökning: "bioinformatics"

Visar resultat 1 - 5 av 103 uppsatser innehållade ordet bioinformatics.

  1. 1. Neural networks for imputation of missing genotype data : An alternative to the classical statistical methods in bioinformatics

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Alfred Andersson; [2020]
    Nyckelord :genetics; imputation; bioinformatics; neural networks; GWAS;

    Sammanfattning : In this project, two different machine learning models were tested in an attempt at imputing missing genotype data from patients on two different panels. As the integrity of the patients had to be protected, initial training was done on data simulated from the 1000 Genomes Project. LÄS MER

  2. 2. Transcriptional changes in stem cell-derived cardiomyocytes during extended cell cultures

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Michel Jonathan Speh; [2020]
    Nyckelord :;

    Sammanfattning : The recent advancement in the field of stem cell research gave rise to high expectations from both general and scientific audiences, and indeed, stem cells and stem cell-derived cells have an enormous potential to forward the fields of medical research and regenerative medicine. Nevertheless, there are still many obstacles and limitations associated with stem cell technology. LÄS MER

  3. 3. Dual RNA-seq analysis of host-pathogen interaction in Eimeria infection of chickens

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Arnar Kári Sigurðarson Sandholt; [2020]
    Nyckelord :Dual RNA-seq; Bioinformatics; Eimeria tenella; Gene co-expression networks; Chicken;

    Sammanfattning : Eimeria tenella is a eukaryotic, intracellular parasite that, along with six other Eimeria species, causes coccidiosis in chickens. This disease can result in weight loss or even death and is estimated to cause 2 billion euros of damages to the chicken industry each year. While much is known of the life cycle of E. LÄS MER

  4. 4. Causality in Coexpression

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Carolina Barros; [2020]
    Nyckelord :bioinformatics; computational biology; genomics; causality; genetics; coexpression;

    Sammanfattning : One of the main goals of genetics has been to understand the link between genotype and phenotype. Using yeast (Saccharomyces cerevisiae) as our model organism, we take a closer look at the connection between genetic variation and gene expression to learn more about the mechanisms of gene regulation. LÄS MER

  5. 5. Novel workflow for metagenomics and transcriptomics analysis of A.D. systems

    Master-uppsats, SLU/Dept. of Animal Environment and Health

    Författare :Renaud Van Damme; [2020]
    Nyckelord :Metagenomics; transcriptomics; pipeline; A.D systems; Biogas; Bioinformatics;

    Sammanfattning : The A.D. systems (anaerobic digestion), when used in biogas reactors, are an advanced ecological way to produce energy while treating waste. The majority of the microbial community of the reactor remains unknown to this day, due to the impossibility to culture most of the bacteria individually. LÄS MER