Sökning: "biophysics"

Visar resultat 1 - 5 av 20 uppsatser innehållade ordet biophysics.

  1. 1. Multiple-Emitter Super-resolution Imaging using the Alternating Descent Conditional Gradient Method

    Kandidat-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Författare :Dolev Illouz; [2023]
    Nyckelord :super-resolution; alternating descent conditional gradient method; ADCG; multiple-emitter localization; nanoscale imaging; single molecule tracking; Physics and Astronomy;

    Sammanfattning : This thesis examines the state-of-the-art 2D super-resolution technique alternating descent conditional gradient (ADCG) method's ability to accurately localize fluorophores in diffraction-limited single molecule images (SMI) and analyze the impact of pre-processing and post-processing modules on ADCG's fluorophore localization. A synthetic dataset obtained from the 2013 Grand Challenge localization microscopy and a temporally linked dataset obtained from an unpublished set of Optical DNA mapping experiments performed by Jonathan Jeffet at the NanoBioPhotonix Lab at Tel-Aviv University were initially segmented to extract their noise parameters. LÄS MER

  3. 2. Chemoreception of a Two-Dimensional Cell with Multilayer Diffusion

    Kandidat-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Författare :Steffi Schijf; [2023]
    Nyckelord :biophysics; chemoreception; receptors; multilayer diffusion; diffusion; Physics and Astronomy;

    Sammanfattning : Previously, Berg and Purcell found an expression for the diffusion current of particles into a set of receptors in their paper Physics of Chemoreception. These receptors were assumed to be uniformly distributed on a spherical cell's surface and the receptors where idealized as circular patches. LÄS MER

  4. 3. Approaches to Structural Characterization of a Heteromeric GABA(A)R

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Alexander Stevens; [2023]
    Nyckelord :Applied Physics; Biophysics; Molecular Biophysics; GABA A R; LGIC; pLGIC; Tillämpad Fysik; Biofysik; Molekylär Biofysik; GABA A R; LGIC; pLGIC;

    Sammanfattning : Structural biology has become an important part of researching various diseases and drug development. In this thesis, I provide details on how I worked with approaches to structural characterization of a heteromeric GABA(A)R. LÄS MER

  5. 4. The role of gap junctions in coordination of intercellular Ca2+ signaling

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Emma Latron; [2023]
    Nyckelord :applied physics; biophysics; Calcium; MDCKII; Gap Junctions; signalling; Segmentation; Tillämpad fysik; Biofysik; Kalcium; MDCKII; Gap Junctions; signalering; segmentering;

    Sammanfattning : Calcium ions are one of the most versatile signalling molecules. They are essential tothe proper functioning of various cellular processes in many different types of cells.The calcium signals have been studied in the past using ratiometric dyes like Fura-2. LÄS MER

  7. 5. Monte Carlo Simulations of Oligomerized Na+,K+-ATPase

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Jakob Jönsson; [2022]
    Nyckelord :biophysics; p-type ATPase; enzyme activity; simulation; biofysi; p-typ ATPas; enzym aktivitet; simulering;

    Sammanfattning : Na+,K+-ATPase (NKA) is a membrane protein which assists in maintaining the electrochemical potential across the cell membrane. It has been suggested that the oligomerization of NKA may play a role in intracellular regulation of NKA activity. LÄS MER