Sökning: "carbapenem"
Visar resultat 1 - 5 av 11 uppsatser innehållade ordet carbapenem.
1. The Binding Mechanism of Carbapenems in the Class A beta-lactamase IMI-1 : A Molecular Dynamics Study of Ligand Stability
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/BiokemiSammanfattning : Antibiotic resistance is a global and accelerating matter. Over time, the bacteria have evolved several defense mechanisms against the antibiotics. One of the defense mechanisms is that the bacteria can produce enzymes with the ability to hydrolyze the characteristic b-lactam ring of the antibiotics. These enzymes are called b-lactamases. LÄS MER
2. Pharmacokinetic changes of meropenem in sepsis patients: A Comparative Review
Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaciSammanfattning : Background: Sepsis is a life-threatening organ dysfunction occurring during infections. Meropenem is a hydrophilic β-lactam carbapenem antibiotic. Its pharmacokinetic parameters are expected to change due to sepsis-induced physiological alterations and will thus require altered dosing strategies for optimal treatment of sepsis patients. LÄS MER
3. Screening for carbapenemase-associated biomarkers in Klebsiella oxytoca using matrixassisted laser desorption/ionization time of flight mass spectrom
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : Antibiotic resistant bacteria are threatening human health, and the resistance is progressingfaster than the development of new antimicrobial compounds. Antibiotic resistant infections cost enormous sums of money and resources, but most importantly human lives. LÄS MER
4. Antibiotic combination therapies against carbapenamse producing Klebsiella pneumoniae
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : The treatment options for multidrug resistant bacteria are dwindling and it is an important issue of research in medicine to solve. One of the more problematic bacterial species is Klebsiella pneumoniae, it can cause infections with high morbidity that are difficult to treat. LÄS MER
5. Multi-drug resistant Gram-negative bacteria in wastewater treatment plants : -With focus on Acinetobacter baumannii complex
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : Multidrug-resistant (MDR) pathogens are emerging problems humanity faces today. Increasing MDR Gram-negative bacteria is not only a threat towards humanity itself but also towards food safety. The genus Acinetobacter is an environmental bacterium that can be found in habitats, including aquatic environments, soil, wastewater, food, and animals. LÄS MER