Sökning: "cell Metabolism"

Visar resultat 1 - 5 av 77 uppsatser innehållade orden cell Metabolism.

  1. 1. The Quantitative Expression of Transport Proteins SLC38A1-11 in Nerve Cell Development

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Maryam Dinar; [2023]
    Nyckelord :SLC38A1; SNAT1; SLC38A2; SNAT2; SLC38A3; SNAT3; SLC38A4; SNAT4; SLC38A5; SNAT5; SLC38A6; SNAT6; SLC38A7; SNAT7; SLC38A8; SNAT8; SLC38A9; SNAT9; SLC38A10; SNAT10; SLC38A11; SNAT11; SLC; SLC38; SNATs; SNAT; RT-qPCR; GABA; glutamine; glutamate;

    Sammanfattning : Solute carriers consist of over 400 genes and 66 subfamilies and are the largest group of membrane bound transporters. They facilitate movement of many molecules through cells and organelles and are crucial for upholding many key functions in the human body. They are also involved in the pathophysiology of several diseases. LÄS MER

  3. 2. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Mawj Jasimalsalih; [2023]
    Nyckelord :Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Sammanfattning : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. LÄS MER

  4. 3. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

    Master-uppsats, Lunds universitet/Institutionen för immunteknologi

    Författare :Johan Thorsson; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. LÄS MER

  5. 4. Structural and Functional Characterisation of the Human Mitochondrial Pyruvate Carrier

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Simon Gripvall; [2023]
    Nyckelord :biochemistry; complex; MPC; proteoliposomes; pyruvate; transport; Chemistry;

    Sammanfattning : The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases. LÄS MER

  7. 5. Study of energy metabolism in fibrocytes frommyelofibrosis patients : - a comparison withhealthy individuals

    Kandidat-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Fanny Folkö; [2022]
    Nyckelord :;

    Sammanfattning : Introduction: Myelofibrosis is a rare and deadly disease where bone marrow fibrosisobstructs production of blood cells. Metabolic alterations in cancer cells are well researchedand considered a possible therapeutic target. Few studies have researched the same possibilityfor myelofibrosis. LÄS MER