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Visar resultat 1 - 5 av 28 uppsatser som matchar ovanstående sökkriterier.

  1. 1. Systematic Multi-Parametric Analysis of Acute Myeloid Leukemia (AML) Flow Cytometry Drug Screens using Flowty

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Augusta Jensen; [2023]
    Nyckelord :Acute myeloid leukemia; AML; cellular subpopulations; data analysis; precision medicine; Flowty; applied microbiology; Biology and Life Sciences;

    Sammanfattning : Acute myeloid leukemia (AML) is a heterogeneous disease, making it difficult to treat. The standard treatment is intensive chemotherapy and has not changed in 40 years. However, recently new drugs and as less intensive treatment regimens have been approved in the US and in Europe. However. LÄS MER

  3. 2. Image-Based Classification Solutions for Robust Automated Molecular Biology Labs

    Master-uppsats, KTH/Medicinteknik och hälsosystem

    Författare :Arnold Teo; [2023]
    Nyckelord :Neural networks; Deep learning; Transfer learning; TensorFlow; Single-cell genomics; Image classification; Neurala nätverk; Djupinlärning; Överförd inlärning; TensorFlow; Enskild cellgenomik; Bildklassificering;

    Sammanfattning : Single-cell genomics (SCG) are methods for investigating heterogeneity between biological cells, among these is Smart-seq which sequences from RNA molecules. A more recent version of this method is Smart-seq3xpress which is currently in the process of being automated by the Sandberg lab at Karolinska Institutet. LÄS MER

  4. 3. Can biomarkers identify oral leukoplakia at high risk of malignant transformation? : A systematic review

    Master-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Ronnie Hasan; [2023]
    Nyckelord :Precision medicine; oral neoplasms; brush biopsies; biomarkers; oral leukoplakia.;

    Sammanfattning : Introduction Oral squamous cell carcinomas (OSCCs) frequently develop from oral potentially malignantdisorders (OPMDs). Oral leukoplakia (OL) is a white lesion in the oral mucosa and the mostprevalent OPMD. Malignant transformation rates for OL to OSCC has recently been reportedto 9.8%. LÄS MER

  5. 4. Molecular mapping of the HGSOC tumour microenvironment

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Philippine Louail; [2023]
    Nyckelord :Immunology; Ovarian cancer; Multiplex Immunofluorescence; scRNA sequencing; Bioinformatics; Image analysis;

    Sammanfattning : High-grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer, and its heterogeneity poses a challenge for the discovery of reliable diagnostic biomarkers, therapeutic targets, and predicting treatment response, particularly to immunotherapy. The current standard diagnostic and treatment options are inadequate, resulting in late diagnosis and poor prognosis. LÄS MER

  7. 5. Determining the Acoustic Mobility of Breast Cancer Cells

    Master-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

    Författare :Simon Olsson; [2022]
    Nyckelord :Technology and Engineering;

    Sammanfattning : Breast cancer is one of the most common forms of cancer detected in women. Its heterogeneity and large mutational landscape requires treatment strategies which varies between patients. Triple negative breast cancer (TNBC) is a particularly aggressive subtype which 12-17 \% of breast cancer patient develop. LÄS MER