Sökning: "cell signalling"

Visar resultat 1 - 5 av 57 uppsatser innehållade orden cell signalling.

  1. 1. Cytokine capture with beads in cytotoxicity assays in microwells

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Maxime Simon; [2023]
    Nyckelord :Microbead; Inteferon gamma; Natural Killer cells; microwell; binding-reaction model; Mikrokula; Interferon gamma; Naturliga Mördarceller; Mikrobrunn; modell för bindningsreaktion;

    Sammanfattning : Cytokines are small, secreted proteins that are important for cell signalling in theimmune system. Interferon gamma (IFN-γ) is one of the most potent cytokines thatnatural killer (NK) cells of the innate immune system secrete with both antiviral,antibacterial, and antitumoral activity. LÄS MER

  3. 2. Diffusion and Camera-Noise Modelling for Analysis of Single-Particle Tracking Movies

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Erik Clarkson; [2022]
    Nyckelord :reaction-diffusion; camera-noise modelling; single-particle tracking; Gillespie simulations; Physics and Astronomy;

    Sammanfattning : Interactions between T-cells and other body cells is an essential part of the immune system. It involves the binding between surface receptors of the two cells. Specifically, T-cell receptors (TCRs) bind onto pMHC (peptide-loaded major histocompatibility complex) molecules on the partnering cell surface. LÄS MER

  4. 3. Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

    Magister-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Fredrik Bertilsson; [2022]
    Nyckelord :Biophysics; systems biology; gene regulatory networks; neural tube; isthmic organizer; midbrain-hindbrain boundary; WNT; FGF; morphogens; reaction-diffusion; finite-difference; 3D modelling; Physics and Astronomy;

    Sammanfattning : Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. LÄS MER

  5. 4. A Study on Data-driven Methods for Selection and Evaluation of Beam Subsets in 5G NR

    Master-uppsats, Lunds universitet/Institutionen för elektro- och informationsteknik

    Författare :Nic Ekman; Ilias Theodoros Skordas; [2022]
    Nyckelord :5G; NR; telecom; telecommunications; ML; machine learning; algorithms; beam; widebeam; propagation; beamforming; subset; RAN; radio; radio environment; ericsson; Technology and Engineering;

    Sammanfattning : 5G New Radio is the next generation of mobile networks and it comes with promises of ultra-high speeds, ultra-high reliability and ultra-low latency. This has posed a challenge for the engineers entrusted with the task of finding solutions which could fulfil the specification, and as a result, some promising areas have received increased attention in recent years. LÄS MER

  7. 5. The differential signalling of the succinate receptor SUCNR1/GPR91, through Gi versus Gq

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Sofie Liljewall; [2022]
    Nyckelord :GPR91; SUCNR1; G protein recruitment; Gi; Gq; TRUPATH biosensor; BRET2; Applied Microbiology; Biology and Life Sciences;

    Sammanfattning : G protein-coupled receptors are the biggest family of membrane bound receptor in the human genome, they are also target for many drugs due to their accessible location in the cell membrane. We have characterized the G protein recruitment of the succinate receptor 1 (SUCNR1/GPR91). LÄS MER