Sökning: "cell surface biomarker"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden cell surface biomarker.

  1. 1. Decoding Hormone Interactions: Investigating Health Status Using Hormone Signatures in Blood

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Stina Brunell; Elis Pettersson Gradin; Victor Englöf; Lovisa Wigertz; Embla Persson; Josephine Maglio; [2023]
    Nyckelord :PEA; hormone; interaction; blood; protein hormone; proteomic; disease; biomarker;

    Sammanfattning : Hormones are integral molecules in the human body, controlling most body systems and maintaining homeostasis in the body. They function as signal molecules for communication between cells, and are often secreted by one tissue with another as target. LÄS MER

  3. 2. Generation of a new ADAPT library for stability improvement

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Sumant Yogesh Salphale; [2023]
    Nyckelord :Phage display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; protein engineering; cancer detection; Fag-display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; proteinteknik; cancerdetektion;

    Sammanfattning : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. LÄS MER

  4. 3. Improving antibody-based immunotherapy protocols in vitro : Study on optimization of antitumor immunity by antibody-dependent phagocytosis with the monoclonal antibody rituximab

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Giovanni Ferro; [2022]
    Nyckelord :;

    Sammanfattning : The monoclonal antibody Rituximab (RTX) has been widely and successfully used to treat non-Burkitt B cell lymphoma in human patients. The combination of immunotherapy with low-dose chemotherapy has increased the success of the treatment and translated into increased patients’ survival. LÄS MER

  5. 4. Study of pH effect on the skin in Franz cell by impedance spectroscopy: an attempt to model incontinence effect on the skin.

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Megha Bhavinkumar Patel; [2022]
    Nyckelord :Artificial urine; Electrical impedance spectroscopy EIS ; Incontinence-associated dermatitis IAD ; pH; Stratum corneum SC ; Artificial urine; Electrical impedance spectroscopy EIS ; Incontinence-associated dermatitis IAD ; pH; Stratum corneum SC ;

    Sammanfattning : The human skin is the largest and most complex body organ but accessible and attractive for biomarker sampling and transdermal drug delivery. The two procedures are significantly impacted by several biophysical properties of the skin, especially the pH and stratum corneum (SC)hydration. LÄS MER

  7. 5. Local, intestinal biomarkers for early detection of colorectal cancer

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Martina Andersson; [2021]
    Nyckelord :crc; biomarkers; colorectal cancer; cell surface biomarker;

    Sammanfattning : Colorectal cancer (CRC) is one of the deadliest cancers in the world. The early stage of the disease is usually asymptomatic and therefore screening methods for colorectal cancer need to improve. There is a need for early detection of CRC as treatment is less effective in the advanced stage of the disease. LÄS MER