Sökning: "cellbiologi"

Visar resultat 1 - 5 av 51 uppsatser innehållade ordet cellbiologi.

  1. 1. Evaluating the Accuracy of Chloride Meters, The ChloroChek instrument in Sweat Testing for Cystic Fibrosis

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Hawa Abshir; [2023]
    Nyckelord :Pilocarpine iontophoresis; coulometric titration; CFTR-mutations; salt consumption and sweat storage.;

    Sammanfattning : Background: Cystic fibrosis (CF) is a hereditary disorder caused by genetic mutations, which affect the chloride ion channels, leading to disrupted salt balance in different organs. A lack of properly functioning chloride ion channels can lead to formation of thick mucus, which hinders organ function, especially in the lungs where repeated inflammation occurs. LÄS MER

  2. 2. Gene expression editing in myeloma cell lines using CRISPR/Cas9 technique

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Wilma Wadman; [2023]
    Nyckelord :BMPR1A; BMPR2; bone morphogenetic protein; gene knockout; multiple myeloma;

    Sammanfattning : Multiple myeloma, or myeloma, is a bone marrow cancer which characterizes by uncontrolled proliferation of mutant plasma cells. It is a disease that claims many lives every year, mostly due to the absence of curative treatment. Finding a suitable treatment is therefor of great importance. LÄS MER

  3. 3. Dysbiosis of the urinary microbiome - a potential cause for cystitis in women

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Sandra Näslund; [2023]
    Nyckelord :Enhanced quantitative urine culture; Lactobacillus; MALDI-TOF MS; microbiota; urinary tract infection;

    Sammanfattning : Background: Urinary tract infection (UTI) is a common bacterial infection that is usually diagnosed by symptoms such as dysuria and frequency, and the golden standard is to take a urine culture to identify bacteria that may cause UTI. This method was founded with the idea that normal urine is sterile, but this is now being questioned because of growing evidence of a urinary microbiota thus giving a new approach to methods for UTI diagnosis. LÄS MER

  4. 4. Method development of magnetic cell isolation and DNA extraction of small cell populations from Ficoll-separated hematopoietic cells

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Dominika Debowska; [2023]
    Nyckelord :Clonal haematopoiesis of indeterminate potential CHIP ; hematopoietic stem cell; automated cell separation; silica-membrane-based nucleic acid purification.;

    Sammanfattning : Clonal haematopoiesis of indeterminate potential, or CHIP are a family of mutations present in the general population. CHIP-mutations are prevalent in the haematopoietic stem cells and in the more mature cell populations, T-lymphocytes, B-lymphocytes and myeloid cells (CD3+, CD19+ and CD33+ cells) in blood. LÄS MER

  5. 5. Verifying the analysis of complement component C3 and C4 on Siemens Atellica NEPH 630

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Fanny Engström; [2023]
    Nyckelord :Complement system; nephelometry; C3c; autoimmune diseases; Cobas 6000;

    Sammanfattning : The complement components C3 and C4 are part of the complement system. The complement system has many tasks to perform in the body and consists of several proteins that all have unique tasks. C3 and C4 are examined, for example, if a deficiency is suspected, in the presence of autoimmune diseases or in the case of recurring bacterial infections. LÄS MER