Sökning: "computational biology"

Visar resultat 1 - 5 av 33 uppsatser innehållade orden computational biology.

  1. 1. Simulate Bacterial Movement through Chemotaxis

    Kandidat-uppsats, Göteborgs universitet/Institutionen för data- och informationsteknik

    Författare :Rasmus Durgé; Johan Ek; Jonny Fredriksson; Emil Logren; Mohamad Melhem; Rik Muijs; [2021-09-14]
    Nyckelord :chemotaxis; computational biology; agent-based simulation; Unity engine;

    Sammanfattning : This thesis describes the development of an agent-based simulation of E. coli chemotaxis in C# and the Unity game engine. The agents use a mathematical modelof the chemical pathway underlying chemotaxis to produce either forward-motion(running) or rotation (tumbling), in response to the concentration of ligand in theirimmediate environment. LÄS MER

  2. 2. Exploring Flow Cytometry for Monitoring of Microbial Water Quality During Maintenance of Drinking Water Pipes

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Måns Zamore; [2021]
    Nyckelord :flow cytometry; microbiology; drinking water; applied microbiology; Biology and Life Sciences;

    Sammanfattning : Faster methods of analysing microbial drinking water quality after pipe breaks or new pipe installations would have beneficial implications. This thesis investigates the use of flow cytometry and cultivation-based techniques in connection to maintenance works, and how flow cytometry can aid in the decision-making around putting drinking water pipes in operation. LÄS MER

  3. 3. Exploring DeepSEA CNN and DNABERT for Regulatory Feature Prediction of Non-coding DNA

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Jacob Stachowicz; [2021]
    Nyckelord :Machine Learning; Computer Science; Bioinformatics; Genomics; Transformer; Natural Language Processing; Whole Genome Sequencing; Non-codingDNA; DeepSEA; CNN; DNABert; BERT; DanQ; Biomedical Science; Computational Biology; AuROC; AUPRC; Maskininlärning; Datavetenskap; Bioinformatik; Genomik; Transformer; Språkteknologi; Helgenomsekvensering; icke-kod DNA; DeepSEA; CNN; DNABert; BERT; DanQ; Biomedicinsk vetenskap; Beräkningsbiologi; AuROC; AUPRC;

    Sammanfattning : Prediction and understanding of the regulatory effects of non-coding DNA is an extensive research area in genomics. Convolutional neural networks have been used with success in the past to predict regulatory features, making chromatin feature predictions based solely on non-coding DNA sequences. LÄS MER

  4. 4. Causality in Coexpression

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Carolina Barros; [2020]
    Nyckelord :bioinformatics; computational biology; genomics; causality; genetics; coexpression;

    Sammanfattning : One of the main goals of genetics has been to understand the link between genotype and phenotype. Using yeast (Saccharomyces cerevisiae) as our model organism, we take a closer look at the connection between genetic variation and gene expression to learn more about the mechanisms of gene regulation. LÄS MER

  5. 5. A parallel implementation of spatially distributed stochastic chemical kinetics

    Kandidat-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Pontus Melin; [2020]
    Nyckelord :;

    Sammanfattning : Stochastic simulation of reaction kinetics has emerged as animportant computational tool in molecular systems biology and will likely continue to grow in importance as experimental techniques are further developed and spatial models can be calibrated to biological data. Many applications require a large number of sample realizations to be generated in order to allow for useful statistical analysis. LÄS MER